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  • DC Chemicals Limited
  • China
  • Product Name: IWP12
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

688353-45-9

688353-45-9 structure
688353-45-9 structure
  • Name: IWP 12
  • Chemical Name: IWP-12
  • CAS Number: 688353-45-9
  • Molecular Formula: C18H18N4O2S3
  • Molecular Weight: 418.556
  • Create Date: 2021-01-30 08:12:23
  • Modify Date: 2024-01-18 20:51:37
  • IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autonomous Wnt signaling with an IC50 of 15 nM[1].

Name IWP-12
Synonyms 2-[(3,6-Dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide
Acetamide, N-(6-methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3,6-dimethyl-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-
IWP-12
Description IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autonomous Wnt signaling with an IC50 of 15 nM[1].
Related Catalog
References

[1]. Wang X, et al. The development of highly potent inhibitors for porcupine. J Med Chem. 2013 Mar 28;56(6):2700-4.

Density 1.6±0.1 g/cm3
Molecular Formula C18H18N4O2S3
Molecular Weight 418.556
Exact Mass 418.059174
LogP 3.99
Index of Refraction 1.783
RIDADR NONH for all modes of transport