4-(Hydroxymethyl)phenoxyacetic acid structure
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Common Name | 4-(Hydroxymethyl)phenoxyacetic acid | ||
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CAS Number | 68858-21-9 | Molecular Weight | 182.173 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 378.3±22.0 °C at 760 mmHg | |
Molecular Formula | C9H10O4 | Melting Point | 112-114 °C | |
MSDS | Chinese USA | Flash Point | 156.3±15.8 °C |
Use of 4-(Hydroxymethyl)phenoxyacetic acid4-(Hydroxymethyl)phenoxyacetic acid is an acid-labile resin linkage agent for use in solid phase peptide synthesis[1]. |
Name | 4-(Hydroxymethyl)phenoxyacetic acid |
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Synonym | More Synonyms |
Description | 4-(Hydroxymethyl)phenoxyacetic acid is an acid-labile resin linkage agent for use in solid phase peptide synthesis[1]. |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 378.3±22.0 °C at 760 mmHg |
Melting Point | 112-114 °C |
Molecular Formula | C9H10O4 |
Molecular Weight | 182.173 |
Flash Point | 156.3±15.8 °C |
Exact Mass | 182.057907 |
PSA | 66.76000 |
LogP | 0.16 |
Vapour Pressure | 0.0±0.9 mmHg at 25°C |
Index of Refraction | 1.573 |
Storage condition | 2-8°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
Risk Phrases | R36/37/38 |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2918990090 |
~54% 4-(Hydroxymethy... CAS#:68858-21-9 |
Literature: Atherton, Eric; Logan, Christopher J.; Sheppard, Robert C. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 538 - 546 |
~% 4-(Hydroxymethy... CAS#:68858-21-9 |
Literature: US5187270 A1, ; |
~% 4-(Hydroxymethy... CAS#:68858-21-9 |
Literature: Bioorganic and Medicinal Chemistry, , vol. 16, # 23 p. 10049 - 10060 |
~% 4-(Hydroxymethy... CAS#:68858-21-9 |
Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 538 - 546 |
Precursor 5 | |
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DownStream 4 | |
HS Code | 2918990090 |
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Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Acid-labile resin linkage agents for use in solid phase peptide synthesis.
Int. J. Pept. Protein Res. 20(5) , 451-4, (1982) Details are given of the preparation of two acid-labile peptide-resin linkage agents for use in solid phase peptide synthesis, viz. 4-hydroxymethylphenoxy-acetic acid and 3-methoxy-4-hydroxymethylphen... |
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Improving the performance of an acid-labile 4-hydroxymethyl phenoxyacetic acid (HMP) linker on resin and SynPhase grafted solid-supports.
J. Pept. Sci. 6(10) , 534-8, (2000) A replacement of the acetic acid moiety by valeric acid within the 4-hydroxymethylphenoxyacetic acid (HMP) linker (Sheppard RC, Williams BJ. Acid-labile resin linkage agents for use in solid phase pep... |
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E. Atherton et al.
J. Chem. Soc. Chem. Commun. , 537, (1978)
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HMP Linker |
Acetic acid, 2-[4-(hydroxymethyl)phenoxy]- |
HMPLinker |
2-[4-(hydroxymethyl)phenoxy]acetic acid |
[4-(Hydroxymethyl)phenoxy]acetic acid |
MFCD00057827 |
EINECS 229-560-6 |
HMP-Linker |