SKF 91488 dihydrochloride

Modify Date: 2024-04-05 19:33:47

SKF 91488 dihydrochloride Structure
SKF 91488 dihydrochloride structure
Common Name SKF 91488 dihydrochloride
CAS Number 68941-21-9 Molecular Weight 248.22
Density N/A Boiling Point N/A
Molecular Formula C7H19Cl2N3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SKF 91488 dihydrochloride


SKF 91488 (Homodimaprit) dihydrochloride is a potent and noncompetitive histamine N-methyltransferase inhibitor with a Ki value of 0.9 microM. SKF 91488 dihydrochloride inhibits the methylation of labeled histamine in mice[1].

 Names

Name Homodimaprit dihydrochloride
Synonym More Synonyms

 SKF 91488 dihydrochloride Biological Activity

Description SKF 91488 (Homodimaprit) dihydrochloride is a potent and noncompetitive histamine N-methyltransferase inhibitor with a Ki value of 0.9 microM. SKF 91488 dihydrochloride inhibits the methylation of labeled histamine in mice[1].
Related Catalog
References

[1]. Beaven MA, et, al. Inhibition of histamine methylation in vivo by the dimaprit analog, SKF Compound 91488. Agents Actions. 1979 Dec;9(5-6):455-60.  

 Chemical & Physical Properties

Molecular Formula C7H19Cl2N3S
Molecular Weight 248.22
Exact Mass 211.09100
PSA 78.41000
LogP 2.55690

 Synonyms

S-(4-dimethylamino-butyl)-isothiourea, dihydrochloride
S-(4-Dimethylamino-butyl)-isothioharnstoff, Dihydrochlorid
S-[4-(dimethylamino)butyl]isothiourea dihydrochloride