Aminopicoline
Aminopicoline structure
|
Common Name | Aminopicoline | ||
|---|---|---|---|---|
| CAS Number | 695-34-1 | Molecular Weight | 108.141 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 227.4±20.0 °C at 760 mmHg | |
| Molecular Formula | C6H8N2 | Melting Point | 96-99 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 114.0±9.0 °C | |
| Symbol |
GHS06, GHS08 |
Signal Word | Danger | |
Use of AminopicolineAminopicoline (Ascensil) is a potent and nonselective inhibitor of NO synthase (NOS) isoenzymes (iNOS, nNOS, eNOS)[1]. |
| Name | 4-Methylpyridin-2-amine |
|---|---|
| Synonym | More Synonyms |
| Description | Aminopicoline (Ascensil) is a potent and nonselective inhibitor of NO synthase (NOS) isoenzymes (iNOS, nNOS, eNOS)[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 227.4±20.0 °C at 760 mmHg |
| Melting Point | 96-99 °C(lit.) |
| Molecular Formula | C6H8N2 |
| Molecular Weight | 108.141 |
| Flash Point | 114.0±9.0 °C |
| Exact Mass | 108.068748 |
| PSA | 38.91000 |
| LogP | 1.08 |
| Vapour Pressure | 0.1±0.4 mmHg at 25°C |
| Index of Refraction | 1.574 |
| Water Solubility | SOLUBLE |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS06, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 + H311 + H331-H373 |
| Precautionary Statements | P261-P280-P301 + P310-P311 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T:Toxic |
| Risk Phrases | R25;R36/37/38 |
| Safety Phrases | S53-S45-S60-S61-S37/39-S28A-S26-S36/37/39 |
| RIDADR | UN 3086 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | TJ5150000 |
| Packaging Group | II |
| Hazard Class | 6.1 |
| HS Code | 2932999099 |
|
~80%
Aminopicoline CAS#:695-34-1 |
| Literature: Bruekelman, Stephen P.; Leach, (Miss) Susan E.; Meakins, G. Denis; Tirel, Malcolm D. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 2801 - 2807 |
|
~%
Aminopicoline CAS#:695-34-1 |
| Literature: Journal of Organic Chemistry, , vol. 72, # 12 p. 4554 - 4557 |
|
~95%
Aminopicoline CAS#:695-34-1 |
| Literature: Wachi, Kazuyuki; Terada, Atsusuke Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 10 p. 3020 - 3028 |
|
~%
Aminopicoline CAS#:695-34-1 |
| Literature: Chemische Berichte, , vol. 58, p. 1733 Chemische Berichte, , vol. 58, p. 348 Chemische Berichte, , vol. 57, p. 794 |
|
~%
Aminopicoline CAS#:695-34-1 |
| Literature: Pharmaceutical Chemistry Journal, , vol. 19, # 7 p. 479 - 481 Khimiko-Farmatsevticheskii Zhurnal, , vol. 19, # 7 p. 829 - 832 |
|
~%
Aminopicoline CAS#:695-34-1 |
| Literature: Bioorganic and medicinal chemistry letters, , vol. 10, # 17 p. 1975 - 1978 |
| Precursor 5 | |
|---|---|
| DownStream 10 | |
![2-methoxy-6-[[(4-methylpyridin-2-yl)amino]methylidene]cyclohexa-2,4-dien-1-one structure](https://image.chemsrc.com/caspic/465/106052-58-8.png)
CAS#:106052-58-8![2-[4-(trichloromethyl)pyridin-2-yl]isoindole-1,3-dione structure](https://image.chemsrc.com/caspic/102/106218-68-2.png)
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CAS#:455-69-6| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Guide to Receptors and Channels (GRAC), 4th Edition.
Br. J. Pharmacol. 158 Suppl 1 , S1-254, (2009)
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Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases.
Eur. J. Med. Chem. 44 , 2877-87, (2009) A series of new 3-aroylpyrido[1,2-a]pyrimidines were synthesized from aryl methyl ketones in a simple two-step procedure and evaluated as nitric oxide synthases (NOS) inhibitors. In order to perform a... |
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Actions of 4-methyl-2-aminopyridine on neuromuscular transmission and contractility of skeletal muscle.
Eur. J. Pharmacol. 70(1) , 53-7, (1981) 4-Methyl-2-aminopyridine (4M2AP) increased responses of isolated rat diaphragm and chick biventer cervicis nerve-muscle preparations to nerve stimulation but depressed responses to direct stimulation.... |
| 2-amino-4-Me-pyridine |
| 2-Amino-4-meyhylpyrimidine |
| MFCD00149166 |
| 2-Pyridinamine,4-methyl |
| 4-methyl-pyridin-2-ylamine |
| 4-Methyl-2-aminopyridine |
| 2-Amino-4-methylpyridine |
| 2-Amino-4-picoline |
| 2-amino-4-methyl-pyridine |
| 4-Methylpyridin-2-amin |
| EINECS 234-190-3 |
| Ascensil |
| 4-Methyl-2-pyridylamine |
| 2-Pyridinamine, 4-methyl- |
| 4-PICOLINAMINE |
| 4-PICOLINE,2-AMINO |
| 4-Methyl-2-pyridinamine |
| 4-Methylpyridin-2-amine |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Aminopicoline
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- Purity: 99.0%
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- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Aminopicoline
- Price: ￥108.0/100g ￥338.0/500g
- Purity: 98.0%
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- DC Chemicals Limited
- China
- Product Name: Aminopicoline
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- Purity: 98.0%
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- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 2-Amino-4-picoline
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- Purity: 98.0%
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