Evodine

Modify Date: 2024-01-02 21:24:55

Evodine Structure
Evodine structure
Common Name Evodine
CAS Number 6989-38-4 Molecular Weight 329.347
Density 1.2±0.1 g/cm3 Boiling Point 507.0±50.0 °C at 760 mmHg
Molecular Formula C18H19NO5 Melting Point 153-154ºC
MSDS N/A Flash Point 260.4±30.1 °C

 Use of Evodine


Evodine, the major limonoid of Evodiae Fuctus, is a potent P-gp inhibitor. Evodine has protection against glutamateinduced toxicity by preserving the antioxidant defense system[1].

 Names

Name 1-[(4,8-Dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-3-buten-2 -ol
Synonym More Synonyms

 Evodine Biological Activity

Description Evodine, the major limonoid of Evodiae Fuctus, is a potent P-gp inhibitor. Evodine has protection against glutamateinduced toxicity by preserving the antioxidant defense system[1].
Related Catalog
References

[1]. Xia YY, et al. Simultaneous determination of evodiamine and evodine in Beagle dog plasma using liquidchromatography tandem mass spectrometry. J Asian Nat Prod Res. 2013;15(3):235-43.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 507.0±50.0 °C at 760 mmHg
Melting Point 153-154ºC
Molecular Formula C18H19NO5
Molecular Weight 329.347
Flash Point 260.4±30.1 °C
Exact Mass 329.126312
PSA 73.95000
LogP 3.26
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.612
Storage condition 2-8C

 Synonyms

1-[(4,8-Dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-3-buten-2-ol
3-Buten-2-ol, 1-[(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-
(-)-1'-(2-phenylethylene)-ditryptophenaline
(-)-1-(4,8-dimethoxy-furo[2,3-b]quinolin-7-yloxy)-3-methyl-but-3-en-2-ol
Evodine