Immethridine 2HBr

Modify Date: 2024-04-07 20:52:32

Immethridine 2HBr Structure
Immethridine 2HBr structure
Common Name Immethridine 2HBr
CAS Number 699020-93-4 Molecular Weight 321.01200
Density N/A Boiling Point N/A
Molecular Formula C9H11Br2N3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Immethridine 2HBr


Immethridine dihydrobromide is a selective histamine H3 receptor (H3R) agonist. Immethridine dihydrobromide displays 300-fold selectivity over the H4 receptor and does not bind to H1 or H2 receptors. Immethridine dihydrobromide can be used for experimental autoimmune encephalomyelitis (EAE) research[1].

 Names

Name 4-(1H-Imidazol-5-ylmethyl)pyridine dihydrobromide

 Immethridine 2HBr Biological Activity

Description Immethridine dihydrobromide is a selective histamine H3 receptor (H3R) agonist. Immethridine dihydrobromide displays 300-fold selectivity over the H4 receptor and does not bind to H1 or H2 receptors. Immethridine dihydrobromide can be used for experimental autoimmune encephalomyelitis (EAE) research[1].
Related Catalog
References

[1]. Shi Y, et al. Immethridine, histamine H3-receptor (H3R) agonist, alleviated experimental autoimmune encephalomyelitis via inhibiting the function of dendritic cells. Oncotarget. 2017 Aug 24;8(43):75038-75049.  

 Chemical & Physical Properties

Molecular Formula C9H11Br2N3
Molecular Weight 321.01200
Exact Mass 318.93200
PSA 41.57000
LogP 3.31170