3-Hydroxyphenazepam
Modify Date: 2024-01-02 18:37:57
3-Hydroxyphenazepam structure
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Common Name | 3-Hydroxyphenazepam | ||
|---|---|---|---|---|
| CAS Number | 70030-11-4 | Molecular Weight | 365.61 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 544.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C15H10BrClN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 283.1±30.1 °C | |
Use of 3-Hydroxyphenazepam3-Hydroxyphenazepam is an active metabolite of Cinazepam. Cinazepam is a GABAA receptor agonist. 3-Hydroxyphenazepam can inhibit synaptosomal transporter-mediated [3H]GABA uptake[1]. |
| Name | 7-bromo-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | 3-Hydroxyphenazepam is an active metabolite of Cinazepam. Cinazepam is a GABAA receptor agonist. 3-Hydroxyphenazepam can inhibit synaptosomal transporter-mediated [3H]GABA uptake[1]. |
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| Related Catalog | |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 544.5±50.0 °C at 760 mmHg |
| Molecular Formula | C15H10BrClN2O2 |
| Molecular Weight | 365.61 |
| Flash Point | 283.1±30.1 °C |
| Exact Mass | 363.961395 |
| PSA | 65.18000 |
| LogP | 2.46 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.712 |
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~38%
3-Hydroxyphenazepam CAS#:70030-11-4 |
| Literature: Davidenko, T. I.; Zabolotskaya, N. N.; Milienko, N. P.; Andronati, S. A.; Kuznetsov, V. D.; Bogatskii, A. V. Doklady Chemistry, 1984 , vol. 278, p. 335 - 337 Dokl. Akad. Nauk SSSR Ser. Khim., 1984 , vol. 278, # 4 p. 878 - 881 |
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~%
Detail
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| Literature: Golovenko, N. Ya.; Zin'kovskii, V. G.; Bogatskii, A. V.; Sharbatyan, P. A.; Andronati, S. A. Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 4 p. 208 - 213 Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 4 p. 15 - 21 |
![7-bromo-5-(2-chloro-3-hydroxyphenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one structure](https://www.chemsrc.com/caspic/213/74077-27-3.png)
![7-bromo-5-(2-chlorophenyl)-9-hydroxy-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one structure](https://www.chemsrc.com/caspic/175/74077-28-4.png)
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| 3-Hydroxyfenazepam |
| 7-bromo-5-(2-chlorophenyl)-3-hydroxy-1,2-dihydro-3H-1,4-benzodiazepin-2-one |
| 3-Oxyfenazepam |
| 7-bromo-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one |
| 7-Bromo-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one |
| 3-Hydroxyphenazepam |
| 2H-1,4-Benzodiazepin-2-one, 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy- |