16,24-Cyclo-13,14-secoergost-2-ene-18,26-dioic acid, 5-chloro-14,17:14,27-diepoxy-6,13,20,22-tetrahydroxy-1,15-dioxo-, .gamma.-lactone .delta.-lactone
Modify Date: 2024-01-15 11:04:09
16,24-Cyclo-13,14-secoergost-2-ene-18,26-dioic acid, 5-chloro-14,17:14,27-diepoxy-6,13,20,22-tetrahydroxy-1,15-dioxo-, .gamma.-lactone .delta.-lactone structure
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Common Name | 16,24-Cyclo-13,14-secoergost-2-ene-18,26-dioic acid, 5-chloro-14,17:14,27-diepoxy-6,13,20,22-tetrahydroxy-1,15-dioxo-, .gamma.-lactone .delta.-lactone | ||
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| CAS Number | 70241-09-7 | Molecular Weight | 562.99300 | |
| Density | 1.59g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C28H31ClO10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 16,24-Cyclo-13,14-secoergost-2-ene-18,26-dioic acid, 5-chloro-14,17:14,27-diepoxy-6,13,20,22-tetrahydroxy-1,15-dioxo-, .gamma.-lactone .delta.-lactonePhysalin H is a natural product that can be isolated from Solanum nigrum. Physalin H is an inhibitor of Hedgehog (Hh) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC50 value of 0.7 μM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC50 values of 5.7 and 6.8 μM, respectively[1]. |
| Name | ag-g-74260 |
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| Description | Physalin H is a natural product that can be isolated from Solanum nigrum. Physalin H is an inhibitor of Hedgehog (Hh) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC50 value of 0.7 μM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC50 values of 5.7 and 6.8 μM, respectively[1]. |
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| Related Catalog | |
| References |
| Density | 1.59g/cm3 |
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| Molecular Formula | C28H31ClO10 |
| Molecular Weight | 562.99300 |
| Exact Mass | 562.16100 |
| PSA | 145.66000 |
| LogP | 0.96910 |
| Index of Refraction | 1.66 |
| Hazard Codes | Xi |
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