Methyl Kakuol

Modify Date: 2024-01-30 11:07:21

Methyl Kakuol structure	Common Name	Methyl Kakuol
	CAS Number	70342-29-9	Molecular Weight	208.21100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Methyl Kakuol

Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM[1].

Name	1-(6-methoxy-1,3-benzodioxol-5-yl)propan-1-one
Synonym	More Synonyms

Description	Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Neurological Disease
Target	TRPA1
In Vivo	The maximum concentration (Cmax) of Methyl kakuol at a dose of 2 g/kg (containing 1156 µg/kg, 294 µg/kg, 452 µg/kg, 852 µg/kg asarinin, sesamin, methyl kakuol, and amide A, respectively) is 98.2 ng/mL[1].
References	[1]. Takashi Matsumoto, et al. In Vivo Pharmacokinetic Analysis Utilizing Non-Targeted and Targeted Mass Spectrometry and In Vitro Assay against Transient Receptor Potential Channels of Maobushisaishinto and Its Constituent Asiasari Radix. Molecules. 2020 Sep 18;25(18):4283.

Molecular Formula	C₁₁H₁₂O₄
Molecular Weight	208.21100
Exact Mass	208.07400
PSA	44.76000
LogP	2.01660
Storage condition	2-8°C

1-Propanone,1-(6-methoxy-1,3-benzodioxol-5-yl)

Methyl kakuol

DC Chemicals Limited
China
Product Name: Methyl kakuol
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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