Methyl Kakuol

Modify Date: 2024-01-30 11:07:21

Methyl Kakuol Structure
Methyl Kakuol structure
Common Name Methyl Kakuol
CAS Number 70342-29-9 Molecular Weight 208.21100
Density N/A Boiling Point N/A
Molecular Formula C11H12O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methyl Kakuol


Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM[1].

 Names

Name 1-(6-methoxy-1,3-benzodioxol-5-yl)propan-1-one
Synonym More Synonyms

 Methyl Kakuol Biological Activity

Description Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM[1].
Related Catalog
Target

TRPA1

In Vivo The maximum concentration (Cmax) of Methyl kakuol at a dose of 2 g/kg (containing 1156 µg/kg, 294 µg/kg, 452 µg/kg, 852 µg/kg asarinin, sesamin, methyl kakuol, and amide A, respectively) is 98.2 ng/mL[1].
References

[1]. Takashi Matsumoto, et al. In Vivo Pharmacokinetic Analysis Utilizing Non-Targeted and Targeted Mass Spectrometry and In Vitro Assay against Transient Receptor Potential Channels of Maobushisaishinto and Its Constituent Asiasari Radix. Molecules. 2020 Sep 18;25(18):4283.

 Chemical & Physical Properties

Molecular Formula C11H12O4
Molecular Weight 208.21100
Exact Mass 208.07400
PSA 44.76000
LogP 2.01660
Storage condition 2-8°C

 Synonyms

1-Propanone,1-(6-methoxy-1,3-benzodioxol-5-yl)
Methyl kakuol
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