5(S)​-​HPETE

Modify Date: 2024-01-14 14:40:50

5(S)​-​HPETE Structure
5(S)​-​HPETE structure
Common Name 5(S)​-​HPETE
CAS Number 71774-08-8 Molecular Weight 336.466
Density 1.0±0.1 g/cm3 Boiling Point 518.0±50.0 °C at 760 mmHg
Molecular Formula C20H32O4 Melting Point N/A
MSDS N/A Flash Point 175.6±23.6 °C

 Use of 5(S)​-​HPETE


5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. 5(S)-HpETE is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs.

 Names

Name 5(s)-hpete
Synonym More Synonyms

 5(S)​-​HPETE Biological Activity

Description 5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. 5(S)-HpETE is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs.
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 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 518.0±50.0 °C at 760 mmHg
Molecular Formula C20H32O4
Molecular Weight 336.466
Flash Point 175.6±23.6 °C
Exact Mass 336.230072
PSA 66.76000
LogP 6.38
Vapour Pressure 0.0±3.1 mmHg at 25°C
Index of Refraction 1.513

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JX3867000
CHEMICAL NAME :
6,8,11,14-Eicosatetraenoic acid, 5-hydroperoxy-, (S-(E,Z,Z,Z))-
CAS REGISTRY NUMBER :
71774-08-8
LAST UPDATED :
199506
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C20-H32-O4
MOLECULAR WEIGHT :
336.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Human Cells - not otherwise specified
DOSE/DURATION :
50 umol/L
REFERENCE :
DEOND5 Developments in Oncology. (Kluwer Academic Publishers, POB 358, Accord Stn., Hingham, MA 02018-0358) V.1- 1980- Volume(issue)/page/year: 67,73,1991

 Safety Information

Hazard Codes F: Flammable;Xi: Irritant;
Risk Phrases 11-36/37/38
Safety Phrases 16-26-36
RIDADR UN 1170 3/PG 2

 Synonyms

6,8,11,14-Eicosatetraenoic acid, 5-hydroperoxy-, (5S,6E,8Z,11Z,14Z)-
(5S,6E,8Z,11Z,14Z)-5-hydroperoxyicosa-6,8,11,14-tetraenoic acid
5(S)-HPETE
5S-HpETE
(5S,6E,8Z,11Z,14Z)-5-Hydroperoxy-6,8,11,14-icosatetraenoic acid
5-Hydroperoxy-6,8,11,14-eicosatetraenoic acid
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