5-Hydroxymethyl-2’-deoxycytidine

Modify Date: 2024-01-01 23:02:23

5-Hydroxymethyl-2’-deoxycytidine Structure
5-Hydroxymethyl-2’-deoxycytidine structure
 Common Name 5-Hydroxymethyl-2’-deoxycytidine
CAS Number 7226-77-9 Molecular Weight 337.22300
Density N/A Boiling Point N/A
Molecular Formula C10H16N3O8P Melting Point 205 °C
MSDS N/A Flash Point N/A

 Use of 5-Hydroxymethyl-2’-deoxycytidine


5-Hydroxymethyl-2’-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA. 5-Hydroxymethyl-2’-deoxycytidine may serve as a marker of irreversibly damaged cells[1][2].

 Names

Name 5-(Hydroxymethyl)-2’-deoxycytidine
Synonym More Synonyms

 5-Hydroxymethyl-2’-deoxycytidine Biological Activity

Description 5-Hydroxymethyl-2’-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA. 5-Hydroxymethyl-2’-deoxycytidine may serve as a marker of irreversibly damaged cells[1][2].
Related Catalog
References

[1]. Ewelina Zarakowska, et al. Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice. J Gerontol A Biol Sci Med Sci. 2018 Jul 9;73(8):1003-1009.

[2]. Shuo Liu, et al. Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA. Nucleic Acids Res. 2013 Jul;41(13):6421-9.

 Chemical & Physical Properties

Melting Point 205 °C
Molecular Formula C10H16N3O8P
Molecular Weight 337.22300
Exact Mass 337.06800
PSA 187.17000

 Synthetic Route

 Synonyms

5-hydroxymethyl-2,4-dimethyl-pyrrole-3-carboxylic acid ethyl ester
5-(Hydroxymethyl)-2'-deoxycytidine
5-Hydroxymethyl-2,4-dimethyl-pyrrol-3-carbonsaeure-aethylester
5-Hydroxymethyl-2,4-dimethyl-3-pyrrolcarbonsaeure-ethylester
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