4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE
![4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE Structure](https://www.chemsrc.com/caspic/015/7279-75-6.png)
4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE structure
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Common Name | 4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE | ||
|---|---|---|---|---|
| CAS Number | 7279-75-6 | Molecular Weight | 335.41600 | |
| Density | N/A | Boiling Point | 429.3ºC at 760 mmHg | |
| Molecular Formula | C14H25NO6S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 156.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATEIsoetharine (Isoetarine) mesylate is an orally active selective agonist of β-adrenergic receptors. Isoetharine mesylate is a catechol-like drug and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine mesylate can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2]. |
| Name | 4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol,methanesulfonic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Isoetharine (Isoetarine) mesylate is an orally active selective agonist of β-adrenergic receptors. Isoetharine mesylate is a catechol-like drug and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine mesylate can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2]. |
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| Related Catalog | |
| In Vitro | Isoetharine mesylate (50 μM, 18 hours) can induce the production and release of [35S]sulfated metabolites of catecholic drugs in HepG2 human hepatoma cells[1]. |
| In Vivo | Isoetharine mesylate inhibits melanin deposition with the AC50 value of 5.10 mM and complete inhibition of pigment production at 7.50 mM in the zebrafish larvae model[2]. |
| References |
| Boiling Point | 429.3ºC at 760 mmHg |
|---|---|
| Molecular Formula | C14H25NO6S |
| Molecular Weight | 335.41600 |
| Flash Point | 156.7ºC |
| Exact Mass | 335.14000 |
| PSA | 135.47000 |
| LogP | 2.88350 |
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Nitric oxide and beta-adrenergic agonist-induced bronchial arterial vasodilation.
J. Appl. Physiol. 82 , 686-692, (1997) In anesthetized sheep, we measured bronchial blood flow (Qbr) by an ultrasonic flow probe to investigate the interaction between inhaled nitric oxide (NO; 100 parts/million) given for 5 min and 5 ml o... |
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Non-cAMP-mediated bronchial arterial vasodilation in response to inhaled beta-agonists.
J. Appl. Physiol. 84 , 215-221, (1998) We studied the dose-dependent effects of inhaled isoetharine HCl, a beta-adrenergic bronchodilator (2.5, 5.0, 10.0, and 20.0 mg), on bronchial blood flow (Qbr) in anesthetized sheep. Isoetharine resul... |
| Isoetharine mesylate salt |
| 4-[1-Hydroxy-2-[(1-methylethyl)amino]butyl]-1,2-benzenediol mesylate salt |
| EINECS 230-695-8 |
| 1,2-Benzenediol,4-(1-hydroxy-2-((1-methylethyl)amino)-butyl)-,methanesulfonate (salt) |
| Isotharine mesylate |
| ISOETHARINE MESYLATE |
| Isoetharine mesylate (USP) |
| Isoetarine mesilate |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE
- Price: Negotiable
- Purity: 95.0%
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- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
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- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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