Zenidolol

Modify Date: 2024-01-07 08:07:36

Zenidolol Structure
Zenidolol structure
Common Name Zenidolol
CAS Number 72795-26-7 Molecular Weight 277.40200
Density N/A Boiling Point N/A
Molecular Formula C17H27NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Zenidolol


Zenidolol (ICI-118551) is a selective β2 adrenergic receptor antagonist. Zenidolol inhibits β2-, β1- and β3-adrenergic receptor with Ki values of 0.7, 49.5 and 611 nM, respectively. Zenidolol can be used as an ocular hypotensive agent used for ophthalmic disease research[1].

 Names

Name erythro-(+/-)-(7-methylindan-4-yloxy)-3-isopropylaminobutan-2-ol
Synonym More Synonyms

 Zenidolol Biological Activity

Description Zenidolol (ICI-118551) is a selective β2 adrenergic receptor antagonist. Zenidolol inhibits β2-, β1- and β3-adrenergic receptor with Ki values of 0.7, 49.5 and 611 nM, respectively. Zenidolol can be used as an ocular hypotensive agent used for ophthalmic disease research[1].
Related Catalog
References

[1]. Hoffmann C, et al. Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol. 2004 Feb;369(2):151-9.  

 Chemical & Physical Properties

Molecular Formula C17H27NO2
Molecular Weight 277.40200
Exact Mass 277.20400
PSA 41.49000
LogP 3.00080

 Synonyms

(+/-)-3-isopropylamino-1-(7-methylindan-4-yloxy)butan-2-ol
(2R,3R)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol
erythro-DL-1-(7-Methylindan-4-yloxy)-3-isopropylaminobutan-2-ol
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