Tianeptine

Modify Date: 2024-01-13 19:15:36

Tianeptine Structure
Tianeptine structure
Common Name Tianeptine
CAS Number 72797-41-2 Molecular Weight 436.95200
Density 1.38±0.1 g/cm3(Predicted) Boiling Point 609.2±65.0 °C(Predicted)
Molecular Formula C21H25ClN2O4S Melting Point 129-131℃
MSDS N/A Flash Point N/A

 Use of Tianeptine


Tianeptine is a selective facilitator of 5-HT uptake in vitro and in vivo. IC50 Value: N/ATarget: 5-HT ReceptorTianeptine has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50 > 10 μM) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration in vivo.

 Names

Name 7-[(3-Chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]th iazepin-11-yl)amino]heptanoic acid
Synonym More Synonyms

 Tianeptine Biological Activity

Description Tianeptine is a selective facilitator of 5-HT uptake in vitro and in vivo. IC50 Value: N/ATarget: 5-HT ReceptorTianeptine has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50 > 10 μM) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration in vivo.
Related Catalog
References

[1]. Broqua P; Baudrie V; Chaouloff F Differential effects of the novel antidepressant tianeptine on L-5-hydroxytryptophan (5-HTP)-elicited corticosterone release and body weight loss. Eur Neuropsychopharmacol. 1992 Jun;2(2):115-20.

 Chemical & Physical Properties

Density 1.38±0.1 g/cm3(Predicted)
Boiling Point 609.2±65.0 °C(Predicted)
Melting Point 129-131℃
Molecular Formula C21H25ClN2O4S
Molecular Weight 436.95200
Exact Mass 436.12200
PSA 95.09000
LogP 5.72930
Storage condition -20℃

 Synonyms

Tianeptine
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