Glycerol-d8

Modify Date: 2024-01-12 13:40:27

Glycerol-d8 Structure
Glycerol-d8 structure
Common Name Glycerol-d8
CAS Number 7325-17-9 Molecular Weight 100.14300
Density 1.371 g/mL at 25ºC Boiling Point 182ºC(lit.)
Molecular Formula C3D8O3 Melting Point 20ºC(lit.)
MSDS Chinese USA Flash Point >230 °F(lit.)

 Use of Glycerol-d8


Glycerol-d8 is the deuterium labeled Glycerol[1].

 Names

Name 1,1,2,3,3-pentadeuterio-1,2,3-trideuteriooxypropane
Synonym More Synonyms

 Glycerol-d8 Biological Activity

Description Glycerol-d8 is the deuterium labeled Glycerol[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Density 1.371 g/mL at 25ºC
Boiling Point 182ºC(lit.)
Melting Point 20ºC(lit.)
Molecular Formula C3D8O3
Molecular Weight 100.14300
Flash Point >230 °F(lit.)
Exact Mass 100.09800
PSA 60.69000
Index of Refraction n20/D 1.466(lit.)

 Safety Information

RIDADR NONH for all modes of transport

 Articles6

More Articles
Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase.

Eur. J. Pharm. Sci. 77 , 180-8, (2015)

In mammalian brain, monoacylglycerol lipase (MAGL) is the primary enzyme responsible for terminating signaling function of the endocannabinoid 2-arachidonoylglycerol (2-AG). Previous in vivo studies w...

Molecular-Level Insight into the Differential Oxidase and Oxygenase Reactivities of de Novo Due Ferri Proteins.

J. Am. Chem. Soc. 137 , 9302-14, (2015)

Using the single-chain due ferri (DFsc) peptide scaffold, the differential oxidase and oxygenase reactivities of two 4A→4G variants, one with two histidines at the diiron center (G4DFsc) and the other...

Distribution of bioactive lipid mediators in human skin.

J. Invest. Dermatol. 135 , 1510-20, (2015)

The skin produces bioactive lipids that participate in physiological and pathological states, including homeostasis, induction, propagation, and resolution of inflammation. However, comprehension of t...

 Synonyms

MFCD00084149
1,2,3-Propanetriol-d8
Glycerol-d8
Glycerin-d8
Deuterated glycerol