Acanthoside B

Modify Date: 2024-01-02 18:32:44

Acanthoside B Structure
Acanthoside B structure
Common Name Acanthoside B
CAS Number 7374-79-0 Molecular Weight 580.578
Density 1.4±0.1 g/cm3 Boiling Point 778.5±60.0 °C at 760 mmHg
Molecular Formula C28H36O13 Melting Point N/A
MSDS N/A Flash Point 424.6±32.9 °C

 Use of Acanthoside B


Acanthoside B is a potential bioactive lignan with anti-inflammatory and anti-amnesic activities. Acanthoside B can be used for alzheimer's disease and lung inflammation research[1]

 Names

Name (+)-syringaresinol β-D-glucoside
Synonym More Synonyms

 Acanthoside B Biological Activity

Description Acanthoside B is a potential bioactive lignan with anti-inflammatory and anti-amnesic activities. Acanthoside B can be used for alzheimer's disease and lung inflammation research[1]
Related Catalog
In Vivo Acanthoside B (oral gavage; 10-20 mg/kg; 7 days prior to Scopolamine injection) attenuates Scopolamine inflicted AD-like amnesic traits by restoring the cholinergic activity, decreasing the endogenous antioxidant status, suppressing neuroinflammation, and activating the TrkB/CREB/BDNF pathway in mice[1]. Animal Model: Scopolamine-induced amnesic mouse model[1] Dosage: 10 mg/kg; 20 mg/kg Administration: oral gavage; 7 days Result: Exhibited an anti-amnesic effect in mice.
References

[1]. Govindarajan Karthivashan, et al. Cognitive-enhancing and ameliorative effects of acanthoside B in a scopolamine-induced amnesic mouse model through regulation of oxidative/inflammatory/cholinergic systems and activation of the TrkB/CREB/BDNF pathway. Food Chem Toxicol. 2019 Jul;129:444-457.

[2]. Ju Hee Lee, et al. Inhibition of Lung Inflammation by Acanthopanax divaricatus var. Albeofructus and Its Constituents. Biomol Ther (Seoul). 2016 Jan;24(1):67-74.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 778.5±60.0 °C at 760 mmHg
Molecular Formula C28H36O13
Molecular Weight 580.578
Flash Point 424.6±32.9 °C
Exact Mass 580.215576
PSA 174.99000
LogP -1.60
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.601

 Safety Information

HS Code 1302199099

 Synthetic Route

~86%

Acanthoside B Structure

Acanthoside B

CAS#:7374-79-0

Literature: Vermes, Barbara; Seligmann, Otto; Wagner, Hildebert Phytochemistry (Elsevier), 1991 , vol. 30, # 9 p. 3087 - 3090

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Acanthoside B Structure

Acanthoside B

CAS#:7374-79-0

Literature: Phytochemistry (Elsevier), , vol. 30, # 9 p. 3087 - 3090

~%

Acanthoside B Structure

Acanthoside B

CAS#:7374-79-0

Literature: Phytochemistry (Elsevier), , vol. 30, # 9 p. 3087 - 3090

~%

Acanthoside B Structure

Acanthoside B

CAS#:7374-79-0

Literature: Phytochemistry (Elsevier), , vol. 30, # 9 p. 3087 - 3090

 Customs

HS Code 1302199099

 Synonyms

(+)-syringaresinol beta-D-glucoside
acanthoside B
ELEUTHEROSIDE B+E
ELEUTHEROSIDE E1
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