Macamide B

Modify Date: 2024-01-06 18:45:32

Macamide B structure	Common Name	Macamide B
	CAS Number	74058-71-2	Molecular Weight	345.56200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₃₉NO	Melting Point	95-96℃
	MSDS	N/A	Flash Point	N/A

Use of Macamide B

N-Benzylpalmitamide is a macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH).

Name	N-benzylhexadecanamide
Synonym	More Synonyms

Description	N-Benzylpalmitamide is a macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH).
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH Signaling Pathways >> Neuronal Signaling >> FAAH Natural Products >> Alkaloid Research Areas >> Others
Target	FAAH[1]
In Vitro	N-Benzylpalmitamide is an inhibitor of fatty acid amide hydrolase (FAAH), and shows 24.8% and 43.8% inhibition on FAAH at 10 μM and 500 μM, respectively[1].
References	[1]. Wu H, et al. Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition. Bioorg Med Chem. 2013 Sep 1;21(17):5188-97.

Melting Point	95-96℃
Molecular Formula	C₂₃H₃₉NO
Molecular Weight	345.56200
Exact Mass	345.30300
PSA	32.59000
LogP	7.62440

Hazard Codes	Xi

Palmitic acid

CAS#:57-10-3

Benzylamine

CAS#:100-46-9

~89%

Macamide B

CAS#:74058-71-2

Literature: Komura, Kenichi; Nakano, Yu; Koketsu, Mamoru Green Chemistry, 2011 , vol. 13, # 4 p. 828 - 831

Myristic acid

CAS#:544-63-8

Benzylamine

CAS#:100-46-9

~86%

Macamide B

CAS#:74058-71-2

Literature: Wu, Hui; Kelley, Charles J.; Pino-Figueroa, Alejandro; Vu, Huyen D.; Maher, Timothy J. Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 17 p. 5188 - 5197

Ethyl palmitate

CAS#:628-97-7

Benzylamine

CAS#:100-46-9

~88%

Macamide B

CAS#:74058-71-2

Literature: Ranu, Brindaban C.; Dutta, Pinak Synthetic Communications, 2003 , vol. 33, # 2 p. 297 - 301

1-(2-sulfanylid...

CAS#:74058-64-3

Benzylamine

CAS#:100-46-9

~95%

Macamide B

CAS#:74058-71-2

Literature: Nagao, Yoshimitsu; Seno, Kaoru; Kawabata, Kohji; Miyasaka, Tadayo; Takao, Sachiko; Fujita, Eiichi Tetrahedron Letters, 1980 , vol. 21, p. 841 - 844 Title/Abstract View citing articles Show Details Nagao, Yoshimitsu; Seno, Kaoru; Kawabata, Kohji; Miyasaka, Tadao; Takao, Sachiko; Fujita, Eiichi Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 7 p. 2687 - 2699

Tripalmitin

CAS#:555-44-2

Benzylamine

CAS#:100-46-9

~96%

Macamide B

CAS#:74058-71-2

Literature: Feairheller, S. H.; Bistline, R. G.; Bilyk, A.; Dudley, R. L.; Kozempel, M. F.; Haas, M. J. Journal of the American Oil Chemists' Society, 1994 , vol. 71, # 8 p. 863 - 866

(Z)-phenyl(pyri...

CAS#:100663-86-3

Benzylamine

CAS#:100-46-9

~97%

Macamide B

CAS#:74058-71-2

phenyl(pyridin-...

CAS#:14178-31-5

Literature: Miyasaka, Tadayo; Noguchi, Shunsaku Chemistry Letters, 1985 , p. 701 - 704

Palmitic acid

CAS#:57-10-3

Macamide B

CAS#:74058-71-2

Literature: Nagao, Yoshimitsu; Seno, Kaoru; Kawabata, Kohji; Miyasaka, Tadayo; Takao, Sachiko; Fujita, Eiichi Tetrahedron Letters, 1980 , vol. 21, p. 841 - 844

Palmitoyl chloride

CAS#:112-67-4

Macamide B

CAS#:74058-71-2

Literature: Miyasaka, Tadayo; Noguchi, Shunsaku Chemistry Letters, 1985 , p. 701 - 704

Benzylamine

CAS#:100-46-9

Palmitoyl chloride

CAS#:112-67-4

Macamide B

CAS#:74058-71-2

Literature: Bowen; Smith Journal of the American Chemical Society, 1940 , vol. 62, p. 3522

Precursor 8
CAS#:57-10-3 Palmitic acid CAS#:100-46-9 Benzylamine CAS#:544-63-8 Myristic acid CAS#:628-97-7 Ethyl palmitate
CAS#:74058-64-3 1-(2-sulfanylid... CAS#:555-44-2 Tripalmitin CAS#:100663-86-3 (Z)-phenyl(pyri... CAS#:112-67-4 Palmitoyl chloride
DownStream 0

N-benzylpalmitamide

N-Benzyl-palmitinamid

N-benzyl-hexadecanamide

N-hexadecanoyl benzylamine

N-Benzyl-palmitamid

N-benzylhexylhexadecanamide

Macamide B

Use of Macamide B

Names

Macamide B Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

Synonyms