m-Chloramphenicol

Modify Date: 2024-01-14 08:15:51

m-Chloramphenicol Structure
m-Chloramphenicol structure
Common Name m-Chloramphenicol
CAS Number 7411-65-6 Molecular Weight 323.12900
Density N/A Boiling Point N/A
Molecular Formula C11H12Cl2N2O5 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Danger

 Use of m-Chloramphenicol


m-Chloramphenicol (m-threo-Chloramphenicol) is an impurity of Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis[1].

 Names

Name M-threo-Chloramphenicol
Synonym More Synonyms

 m-Chloramphenicol Biological Activity

Description m-Chloramphenicol (m-threo-Chloramphenicol) is an impurity of Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis[1].
Related Catalog
References

[1]. Berendsen BJ, et al. Discrimination of eight chloramphenicol isomers by liquid chromatography tandem mass spectrometry in order to investigate the natural occurrence of chloramphenicol. Anal Chim Acta. 2011;700(1-2):78-85.

[2]. Polikanov YS, et al. The Mechanisms of Action of Ribosome-Targeting Peptide Antibiotics. Front Mol Biosci. 2018;5:48. Published 2018 May 14.

 Chemical & Physical Properties

Molecular Formula C11H12Cl2N2O5
Molecular Weight 323.12900
Exact Mass 322.01200
PSA 115.38000
LogP 1.82310
Storage condition 2-8°C

 Safety Information

Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H350
Precautionary Statements P201-P308 + P313
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T
Risk Phrases 45
Safety Phrases 53-45
RIDADR NONH for all modes of transport

 Articles5

More Articles
Influence of dTMP on the phenotypic appearance and intracellular persistence of Staphylococcus aureus.

Infect. Immun. 76(4) , 1333-9, (2008)

Thymidine-dependent small-colony variants (SCVs) of Staphylococcus aureus are frequently associated with persistent and recurrent infections in cystic fibrosis patients. The phenotypic appearance of S...

The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells.

PLoS Biol. 8 , (2010)

The protozoan parasite Theileria inhabits the host cell cytoplasm and possesses the unique capacity to transform the cells it infects, inducing continuous proliferation and protection against apoptosi...

Airtight storage of moist wheat grain improves bioethanol yields.

Biotechnol. Biofuels 2(1) , 16, (2009)

Drying is currently the most frequently used conservation method for cereal grain, which in temperate climates consumes a major part of process energy. Airtight storage of moist feed grain using the b...

 Synonyms

ERYTHRO-M-CHLORAMPHENICOL
m-nitro-threo-Chloramphenicol
M-CHLORAMPHENICOL