Tylosin Tartrate

Modify Date: 2024-01-01 20:27:55

Tylosin Tartrate Structure
Tylosin Tartrate structure
Common Name Tylosin Tartrate
CAS Number 74610-55-2 Molecular Weight 1066.19
Density N/A Boiling Point N/A
Molecular Formula C50H83NO23 Melting Point 128 - 132ºC
MSDS Chinese USA Flash Point N/A

 Use of Tylosin Tartrate


Tylosin Tartrate is an antibiotic with a large macrocyclic lactone ring.Target: AntibacterialTylosin is a bacteriostat food additive used in veterinary medicine. It has a broad spectrum of activity against gram-positive organisms and a limited range of gram-negative organisms. There is no significant evidence that tylosin resistant staphylococci of animal origin have endangered human health. Tylosin is not effective against the gram-negative intestinal flora, which thus does not lead to selection of R-factors by conjugation. From the human medical stand point, there is no reason that precludes the use of tylosin as a fee additive in animal feeds [1]. Minimum inhibitory concentrations for tylosin tartrate and other commonly used antibiotics were determined for 103 isolates. Most (82.61%) of the isolates not exposed to antibiotics in the 3 months before submission were sensitive to tylosin tartrate. These findings suggest that tylosin tartrate warrants further study as a first-line option for the treatment of dogs initially presenting with pyoderma [2].

 Names

Name Tylosin tartrate
Synonym More Synonyms

 Tylosin Tartrate Biological Activity

Description Tylosin Tartrate is an antibiotic with a large macrocyclic lactone ring.Target: AntibacterialTylosin is a bacteriostat food additive used in veterinary medicine. It has a broad spectrum of activity against gram-positive organisms and a limited range of gram-negative organisms. There is no significant evidence that tylosin resistant staphylococci of animal origin have endangered human health. Tylosin is not effective against the gram-negative intestinal flora, which thus does not lead to selection of R-factors by conjugation. From the human medical stand point, there is no reason that precludes the use of tylosin as a fee additive in animal feeds [1]. Minimum inhibitory concentrations for tylosin tartrate and other commonly used antibiotics were determined for 103 isolates. Most (82.61%) of the isolates not exposed to antibiotics in the 3 months before submission were sensitive to tylosin tartrate. These findings suggest that tylosin tartrate warrants further study as a first-line option for the treatment of dogs initially presenting with pyoderma [2].
Related Catalog
References

[1]. Knothe, H., A review of the medical considerations of the use of tylosin and other macrolide antibiotics as additives in animal feeds. Infection, 1977. 5(3): p. 183-7.

[2]. Scott, B.A., et al., Efficacy of tylosin tartrate on canine Staphylococcus intermedius isolates in vitro. Vet Ther, 2010. 11(3): p. E1-7.

 Chemical & Physical Properties

Melting Point 128 - 132ºC
Molecular Formula C50H83NO23
Molecular Weight 1066.19
PSA 364.73000
Storage condition 2-8°C
Water Solubility H2O: 50 mg/mL, clear, yellow-green

 Safety Information

Hazard Codes Xn:Harmful
Risk Phrases R42/43
Safety Phrases S22-S36/37-S45
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2941909000

 Customs

HS Code 2941909000

 Synonyms

TYLOSIN TARTRATE CELL CULTURE TESTED
(2R,3R)-2,3-Dihydroxysuccinic acid - [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy}-2-ethyl-14- hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-3-O-methyl-β-D-allopyranoside (1:1)
Tylosin Tartarte
TYLOSINE TARTRATE
MFCD00056845
desmycosin tartrate
tylosin tartrate soluble powder
Butanedioic acid, 2,3-dihydroxy-, (2R,3R)-, compd. with (4R,5S,6S,7R,9R,11E,13E,15R,16R)-15-[[(6-deoxy-3-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-r ibo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxooxacyclohexadeca-11,13-diene-7-acetaldehyde (1:1)
Tylosin (tartrate)
TYLOSIN TARTRATE(POWDER)
tylosin solution
tylosin hydrogen tartrate
TYLOSIN TARTRATE SALT
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