7H-Furo[3,2-g][1]benzopyran-7-one, 4-hydroxy-9-methoxy-

Modify Date: 2024-01-14 12:18:56

7H-Furo[3,2-g][1]benzopyran-7-one, 4-hydroxy-9-methoxy- Structure
7H-Furo[3,2-g][1]benzopyran-7-one, 4-hydroxy-9-methoxy- structure
Common Name 7H-Furo[3,2-g][1]benzopyran-7-one, 4-hydroxy-9-methoxy-
CAS Number 7471-73-0 Molecular Weight 232.18900
Density 1.484g/cm3 Boiling Point 342.7ºC at 760 mmHg
Molecular Formula C12H8O5 Melting Point N/A
MSDS N/A Flash Point 161.1ºC

 Use of 7H-Furo[3,2-g][1]benzopyran-7-one, 4-hydroxy-9-methoxy-


5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite of Xanthotoxin. Xanthotoxin is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight[1].

 Names

Name 4-hydroxy-9-methoxyfuro[3,2-g]chromen-7-one
Synonym More Synonyms

  Biological Activity

Description 5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite of Xanthotoxin. Xanthotoxin is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight[1].
Related Catalog
References

[1]. Alsharari SD, et al. Pharmacokinetic and Pharmacodynamics Studies of Nicotine After Oral Administration in Mice: Effects of Methoxsalen, a CYP2A5/6 Inhibitor. Nicotine Tob Res. 2014 Jan;16(1):18-25.

 Chemical & Physical Properties

Density 1.484g/cm3
Boiling Point 342.7ºC at 760 mmHg
Molecular Formula C12H8O5
Molecular Weight 232.18900
Flash Point 161.1ºC
Exact Mass 232.03700
PSA 72.81000
LogP 2.25340
Index of Refraction 1.67

 Synthetic Route

~%

7H-Furo[3,2-g][1]benzopyran-7-one, 4-hydroxy-9-methoxy- Structure

7H-Furo[3,2-g][...

CAS#:7471-73-0

Literature: Brokke; Christensen Journal of Organic Chemistry, 1958 , vol. 23, p. 589,594

~%

7H-Furo[3,2-g][1]benzopyran-7-one, 4-hydroxy-9-methoxy- Structure

7H-Furo[3,2-g][...

CAS#:7471-73-0

Literature: Brokke; Christensen Journal of Organic Chemistry, 1958 , vol. 23, p. 589,594

~%

7H-Furo[3,2-g][1]benzopyran-7-one, 4-hydroxy-9-methoxy- Structure

7H-Furo[3,2-g][...

CAS#:7471-73-0

Literature: Brokke; Christensen Journal of Organic Chemistry, 1958 , vol. 23, p. 589,594

 Synonyms

4-Hydroxy-9-methoxy-furo[3,2-g]chromen-7-on
xanthotoxin
4-hydroxy-9-methoxy-7H-furo<3,2-g><1>benzopyran-7-one
4-hydroxy-9-methoxy-furo[3,2-g]chromen-7-one
5-hydroxy-8-methoxypsoralen
5-Hydroxyxanthotoxin
8-methoxy-5-hydroxypsoralen