Methylophiopogonanone B

Modify Date: 2024-01-02 17:25:14

Methylophiopogonanone B Structure
Methylophiopogonanone B structure
 Common Name Methylophiopogonanone B
CAS Number 74805-91-7 Molecular Weight 328.359
Density 1.285 Boiling Point 554.5±49.0 °C at 760 mmHg
Molecular Formula C19H20O5 Melting Point N/A
MSDS N/A Flash Point 201.5±23.3 °C

 Use of Methylophiopogonanone B


Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2].

 Names

Name (3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4 H-chromen-4-one
Synonym More Synonyms

 Methylophiopogonanone B Biological Activity

Description Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2].
Related Catalog
References

[1]. Wang Y, et al. Homoisoflavonoids and the Antioxidant Activity of Ophiopogon japonicus Root.

[2]. Ito Y, et al. A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization. Mol Cell Biochem. 2007 Mar;297(1-2):121-9. Epub 2006 Oct 7.

 Chemical & Physical Properties

Density 1.285
Boiling Point 554.5±49.0 °C at 760 mmHg
Molecular Formula C19H20O5
Molecular Weight 328.359
Flash Point 201.5±23.3 °C
Exact Mass 328.131073
PSA 75.99000
LogP 5.22
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.617

 Safety Information

Hazard Codes Xi

 Synonyms

methylophiopogonanone B
Methyl o-nitrophenylacetate
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-, (3R)-
2-nitrophenylacetic acid methyl ester
(3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4H-chromen-4-one
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