Bisdionin C

Modify Date: 2024-01-12 11:03:14

Bisdionin C structure	Common Name	Bisdionin C
	CAS Number	74857-22-0	Molecular Weight	400.39200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₂₀N₈O₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of Bisdionin C

Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively[1].

Name	1,1'-trimethylenebis[theobromine]
Synonym	More Synonyms

Description	Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	GH18 Chitinases[1]
References	[1]. Schüttelkopf AW, et al. Bisdionin C-a rationally designed, submicromolar inhibitor of family 18 chitinases. ACS Med Chem Lett. 2011;2(6):428-432. Published 2011 Mar 23.