CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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KI1410000
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CHEMICAL NAME :
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Ethane, 1,1-difluoro-
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CAS REGISTRY NUMBER :
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75-37-6
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BEILSTEIN REFERENCE NO. :
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1696900
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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15
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MOLECULAR FORMULA :
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C2-H4-F2
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MOLECULAR WEIGHT :
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66.06
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WISWESSER LINE NOTATION :
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FYF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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>1500 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity)
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TYPE OF TEST :
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LCLo - Lowest published lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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64000 ppm/4H
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LC50 - Lethal concentration, 50 percent kill
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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977 gm/m3/2H
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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2000 ppm/6H/2Y-I
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TOXIC EFFECTS :
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Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - changes in metals, not otherwise specified
MUTATION DATA
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TEST SYSTEM :
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Insect - Drosophila melanogaster
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DOSE/DURATION :
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98 pph/10M
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REFERENCE :
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ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 7,275,1974 *** REVIEWS *** TOXICOLOGY REVIEW FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 18,365,1974 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-HUNGARY:TWA 200 mg/m3;STEL 500 mg/m3 JAN 1993 OEL-RUSSIA:STEL 3000 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82202 No. of Facilities: 36 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 516 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82202 No. of Facilities: 1550 (estimated) No. of Industries: 7 No. of Occupations: 27 No. of Employees: 132833 (estimated) No. of Female Employees: 116164 (estimated)
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