Tetramethylammonium hydroxide

Modify Date: 2024-01-01 20:13:26

Tetramethylammonium hydroxide Structure
Tetramethylammonium hydroxide structure
Common Name Tetramethylammonium hydroxide
CAS Number 75-59-2 Molecular Weight 91.152
Density 0.866 g/mL at 25 °C Boiling Point 110 °C
Molecular Formula C4H13NO Melting Point °C
MSDS Chinese Flash Point 80 °F
Symbol GHS02 GHS05 GHS06 GHS08 GHS09
GHS02, GHS05, GHS06, GHS08, GHS09
Signal Word Danger

 Names

Name Tetramethylammonium hydroxide
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.866 g/mL at 25 °C
Boiling Point 110 °C
Melting Point °C
Molecular Formula C4H13NO
Molecular Weight 91.152
Flash Point 80 °F
Exact Mass 91.099716
PSA 23.06000
LogP 0.14560
Vapour Pressure 17.5 mm Hg ( 20 °C)
Index of Refraction n20/D 1.384
Storage condition 2-8°C
Stability Stable. Flammable. Incompatible with strong oxidizing agents, strong acids.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PA0875000
CHEMICAL NAME :
Methanaminium, N,N,N-trimethyl-, hydroxide
CAS REGISTRY NUMBER :
75-59-2
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C4-H12-N.H-O
MOLECULAR WEIGHT :
91.18
WISWESSER LINE NOTATION :
1K1&1&1 &Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
19 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 28,367,1926
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,688,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570994
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Vascular - BP elevation not characterized in autonomic section
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,688,1948
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
1515 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,681,1948 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1009 No. of Facilities: 48 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 48 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1009 No. of Facilities: 105 (estimated) No. of Industries: 6 No. of Occupations: 16 No. of Employees: 6413 (estimated) No. of Female Employees: 1446 (estimated)

 Safety Information

Symbol GHS02 GHS05 GHS06 GHS08 GHS09
GHS02, GHS05, GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H226-H300 + H310-H314-H331-H370-H372-H411
Precautionary Statements P260-P264-P273-P280-P301 + P310-P302 + P350
Target Organs Liver, thymus gland
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes T:Toxic; C:Corrosive;
Risk Phrases R20/21/22;R34
Safety Phrases S45-S36/37/39-S26-S16-S36/37
RIDADR UN 3286 3/PG 2
WGK Germany 1
RTECS PA0875000
Packaging Group II
Hazard Class 3
HS Code 2923900090

 Synthetic Route

 Customs

HS Code 2923900090
Summary 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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 Synonyms

AR-300-49
tetreamethyl ammonium hydroxide
nmw-w
MFCD00008280
TMAH
TRITONNE
Developer
ocg945
TMNOH
AZ-300MIF
AZ-726
nmd3
EINECS 200-882-9
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