Kukoamine A

Modify Date: 2024-01-05 20:42:24

Kukoamine A Structure
Kukoamine A structure
 Common Name Kukoamine A
CAS Number 75288-96-9 Molecular Weight 530.656
Density 1.2±0.1 g/cm3 Boiling Point 872.1±65.0 °C at 760 mmHg
Molecular Formula C28H42N4O6 Melting Point N/A
MSDS N/A Flash Point 481.2±34.3 °C

 Use of Kukoamine A


Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity[1].

 Names

Name N1,N12-bis(dihydrocaffeoyl)spermine
Synonym More Synonyms

 Kukoamine A Biological Activity

Description Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity[1].
Related Catalog
Target

Ki: 1.8 μM (Trypanothione reductase)[1]

References

[1]. Ponasik JA, et al. Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase. Biochem J. 1995 Oct 15;311 ( Pt 2):371-5.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 872.1±65.0 °C at 760 mmHg
Molecular Formula C28H42N4O6
Molecular Weight 530.656
Flash Point 481.2±34.3 °C
Exact Mass 530.310425
PSA 163.18000
LogP -0.17
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.588

 Synonyms

.N1,N14-bis(dihydrocaffeoyl)spermine
Kukoamine A
N,N'-[butane-1,4-diylbis(iminopropane-3,1-diyl)]bis[3-(3,4-dihydroxyphenyl)propanamide]
bis-dihydrocaffeoylspermine
N,N'-[1,4-Butanediylbis(imino-3,1-propanediyl)]bis[3-(3,4-dihydroxyphenyl)propanamide]
Benzenepropanamide, N,N'-[1,4-butanediylbis(imino-3,1-propanediyl)]bis[3,4-dihydroxy-
.kukoamine A
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Chemsrc provides Kukoamine A(CAS#:75288-96-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Kukoamine A are included as well.>> amp version: Kukoamine A

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