m-PEG8-NHS ester

Modify Date: 2024-01-11 18:30:30

m-PEG8-NHS ester Structure
m-PEG8-NHS ester structure
Common Name m-PEG8-NHS ester
CAS Number 756525-90-3 Molecular Weight 509.54500
Density N/A Boiling Point N/A
Molecular Formula C22H39NO12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG8-NHS ester


m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

 Names

Name (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Synonym More Synonyms

 m-PEG8-NHS ester Biological Activity

Description m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Related Catalog
In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. By Boehnke, et al. Preparation of antibody drug conjugates with NAMPT inhibitors for use in treatment of cancer. Patent WO2019149637A1.

 Chemical & Physical Properties

Molecular Formula C22H39NO12
Molecular Weight 509.54500
Exact Mass 509.24700
PSA 137.52000

 Synonyms

AmbotzPEG1885
4,7,10,13,16,19,22,25-Octaoxahexacosanoic Acid N-Succinimidyl Ester
N-Succinimidyl 4,7,10,13,16,19,22,25-Octaoxahexacosanoate
M2187
MeO-dPEG(8)-NHS
Methyl-PEG8-NHS Ester
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