Somatostatin-25

Modify Date: 2024-01-10 10:59:33

Somatostatin-25 Structure
Somatostatin-25 structure
Common Name Somatostatin-25
CAS Number 76461-17-1 Molecular Weight 2876.298
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C127H191N37O34S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Somatostatin-25


Somatostatin-25 is a endogenous neuropeptide hormone that shows inhibitory activity against secretion of growth hormone.

 Names

Name Somatostatin-25
Synonym More Synonyms

 Somatostatin-25 Biological Activity

Description Somatostatin-25 is a endogenous neuropeptide hormone that shows inhibitory activity against secretion of growth hormone.
Related Catalog
In Vitro Somatostatin-25 (0.1 pM-1 nM) significantly inhibits secretion of growth hormone in the in vitro system, and is 3-14 times more effective than the tetradecapeptide. Somatostatin-25 (0.1 nM-1pM) also inhibits secretion of growth hormone induced by the addition of prostaglandin 2 (PGE2). However, Somatostatin-25 shows no effect on the secretion of prolactin[1].
References

[1]. Brazeau P, et al. High biological activity of the synthetic replicates of somatostatin-28 and somatostatin-25. Regul Pept. 1981 Jan;1(4):255-64.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C127H191N37O34S3
Molecular Weight 2876.298
Exact Mass 2874.351563
LogP -9.95
Index of Refraction 1.694
Storage condition 2-8℃

 Synonyms

L-Seryl-L-asparaginyl-L-prolyl-L-alanyl-L-methionyl-L-alanyl-L-prolyl-L-arginyl-L-α-glutamyl-L-arginyl-L-lysyl-L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-3 1-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26, 29,32,35-undecaazacyclooctatriacontan-37-yl]
MFCD00076771
Glycinamide, L-seryl-L-asparaginyl-L-prolyl-L-alanyl-L-methionyl-L-alanyl-L-prolyl-L-arginyl-L-α-glutamyl-L-arginyl-L-lysyl-L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4- aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-13,25,28-tris(phenylmethyl)-1,2-dithia- 5,8,11,14,17,20,23,26,29,32,35-undecaazacycl
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