Ebelactone A

Modify Date: 2024-01-08 13:36:57

Ebelactone A structure	Common Name	Ebelactone A
	CAS Number	76808-16-7	Molecular Weight	338.48200
	Density	1.011g/cm3	Boiling Point	462.8ºC at 760 mmHg
	Molecular Formula	C₂₀H₃₄O₄	Melting Point	N/A
	MSDS	USA	Flash Point	152.8ºC

Name	ebelactone a
Synonym	More Synonyms

Density	1.011g/cm3
Boiling Point	462.8ºC at 760 mmHg
Molecular Formula	C₂₀H₃₄O₄
Molecular Weight	338.48200
Flash Point	152.8ºC
Exact Mass	338.24600
PSA	63.60000
LogP	3.76870
Index of Refraction	1.483

Ebelactone A MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RQ7730000

CHEMICAL NAME :: 2-Oxetanone, 4-(8-hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecenyl) -3-methyl-, (3S-(3- alpha,4-beta(1R*,3E,5S*,7R*,8S*,9S*)))-

CAS REGISTRY NUMBER :: 76808-16-7

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H34-O4

MOLECULAR WEIGHT :: 338.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 33,1594,1980

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	RQ7730000

Structural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes.

J. Antibiot. 35 , 1495-1499, (1982)

Biosynthetic studies of ebelactone A and B by 13C NMR spectrometry.

J. Antibiot. 35 , 1670, (1982)

Biosynthetic pathways of ebelactone A and B were studied by 13C NMR spectroscopy. By using 13C labeled compounds as precursors it was determined that ebelactone A was derived from one molecule of acet...

Effects of ebelactone B, a lipase inhibitor, on intestinal fat absorption in the rat.

J. Enzym. Inhib. 10(1) , 57-63, (1996)

Ebelactones A and B, natural products from Streptomyces aburaviensis are potent inhibitors of pancreatic lipase. Lipase is the key enzyme required for the absorption of dietary triglycerides (TG). Ebe...

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3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECANOIC-1,3-LACTONE

ebelactone a microbial

3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECENOIC 1,3-LACTONE

3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECEN-3-OLIDE

3,11-DIHYDROXY-2,4,5,6,10,12-HEXAMETHYL-9-OXO-6-TETRADECENOIC 1,3-LACTONE