8-Bromo-cAMP sodium salt

Modify Date: 2024-01-02 12:06:58

8-Bromo-cAMP sodium salt Structure
8-Bromo-cAMP sodium salt structure
Common Name 8-Bromo-cAMP sodium salt
CAS Number 76939-46-3 Molecular Weight 430.08
Density N/A Boiling Point N/A
Molecular Formula C10H10BrN5NaO6P Melting Point N/A
MSDS USA Flash Point N/A

 Use of 8-Bromo-cAMP sodium salt


8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA)[1].

 Names

Name 8-Bromo-cAMP, sodium salt,8-Bromoadenosine-3',5'-cyclicmonophosphatesodiumsalt
Synonym More Synonyms

 8-Bromo-cAMP sodium salt Biological Activity

Description 8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA)[1].
Related Catalog
Target

PKA[1]

In Vitro 8-Bromo-cAMP sodium salt is a brominated derivative of cyclic AMP. 8-Bromo-cAMP sodium salt enhances the efficiency of cellular reprogramming. 8-Bromo-cAMP sodium salt improves the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells. 8-Bromo-cAMP sodium salt inhibits proliferation, induce differentiation and apoptosis in a malignant glioma cell line (A-172) and an esophageal cancer cell line (Eca-109)[1].
References

[1]. Wang Y, et al. A cyclic AMP analog, 8-Br-cAMP, enhances the induction of pluripotency in human fibroblast cells. Stem Cell Rev. 2011 Jun;7(2):331-41.

 Chemical & Physical Properties

Molecular Formula C10H10BrN5NaO6P
Molecular Weight 430.08
Exact Mass 428.944977
PSA 167.48000
LogP 0.96450
Storage condition −20°C
Water Solubility H2O: 100 mg/mL

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3

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 Synonyms

4H-Furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-(6-amino-8-bromo-9H-purin-9-yl)tetrahydro-2-hydroxy-, 2-oxide, sodium salt, (4aR,6R,7R,7aS)- (1:1)
8-BROMOADENOSINE 3':5'-CYCLICMONOPHOSPHA TE SODIUM
CAMP,8-BR,NA
8-BROMOADENOSINE-3',5'-CYCLOPHOSPHATE SODIUM SALT
8-BR-CAMP NA
Sodium (4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-oxide
8-BROMO-CAMP,NA
8-bromoadenosine 3:5-cyclic*monophosphate sodiu
8-BROMO-CAMP,SODIUM SALT
8-BR-CAMP SODIUM SALT
8-Bromoadenosine 3',5'-phosphoric acid sodium salt
MFCD00005844
8-BROM-ADENOSIN-3',5'-CYCLOPHOSPHAT
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