Octopamine hydrochloride

Modify Date: 2024-01-02 18:55:25

Octopamine hydrochloride Structure
Octopamine hydrochloride structure
 Common Name Octopamine hydrochloride
CAS Number 770-05-8 Molecular Weight 189.639
Density N/A Boiling Point 360.7ºC at 760 mmHg
Molecular Formula C8H12ClNO2 Melting Point ~170 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 172ºC
Symbol GHS07
GHS07		 Signal Word Warning

 Use of Octopamine hydrochloride


Octopamine Hydrochloride is an endogenous biogenic amine that is closely related to norepinephrine, and has effects on the adrenergic and dopaminergic systems.Target: Dopamine Receptor; Adrenergic ReceptorOctopamine is present in relatively high concentrations in neuronal as well as in non-neuronal tissues of most invertebrate species studied, and modulates almost every physiological process. Octopamine acts as neurohormone including desensitization of sensory inputs, influence on learning and memory, or regulation of the mood of the animal in the central nervous system. Octopamine is the only neuroactive non-peptide transmitter whose physiological role is restricted to invertebrates, and all octopamine receptors belong to the family of G-protein coupled receptors [1].Octopamine (10 μM) injected into the mushroom body (MB) calyces or the antennal lobe but not the lateral protocerebral lobe produces a lasting, pairing-specific enhancement of extension of the proboscis. Octopamine (10 μM) injected into the MB calyces results in an additional pairing-specific effect, because it does not lead to an acquisition but a consolidation after conditioning [2]. Octopamine treatment significantly elevates levels of octopamine in the brain and caused a significant dose-dependent increase in the number of new foragers. Octopamine treatment is effective only when given to bees old enough to forage, i.e., older than 4 days of age. Octopamine influences division of labor in honey bee colonies [3].

 Names

Name Octopamine hydrochloride
Synonym More Synonyms

 Octopamine hydrochloride Biological Activity

Description Octopamine Hydrochloride is an endogenous biogenic amine that is closely related to norepinephrine, and has effects on the adrenergic and dopaminergic systems.Target: Dopamine Receptor; Adrenergic ReceptorOctopamine is present in relatively high concentrations in neuronal as well as in non-neuronal tissues of most invertebrate species studied, and modulates almost every physiological process. Octopamine acts as neurohormone including desensitization of sensory inputs, influence on learning and memory, or regulation of the mood of the animal in the central nervous system. Octopamine is the only neuroactive non-peptide transmitter whose physiological role is restricted to invertebrates, and all octopamine receptors belong to the family of G-protein coupled receptors [1].Octopamine (10 μM) injected into the mushroom body (MB) calyces or the antennal lobe but not the lateral protocerebral lobe produces a lasting, pairing-specific enhancement of extension of the proboscis. Octopamine (10 μM) injected into the MB calyces results in an additional pairing-specific effect, because it does not lead to an acquisition but a consolidation after conditioning [2]. Octopamine treatment significantly elevates levels of octopamine in the brain and caused a significant dose-dependent increase in the number of new foragers. Octopamine treatment is effective only when given to bees old enough to forage, i.e., older than 4 days of age. Octopamine influences division of labor in honey bee colonies [3].
Related Catalog
References

[1]. Roeder, T., Octopamine in invertebrates. Prog Neurobiol, 1999. 59(5): p. 533-61.

[2]. Hammer, M. and R. Menzel, Multiple sites of associative odor learning as revealed by local brain microinjections of octopamine in honeybees. Learn Mem, 1998. 5(1-2): p. 146-56.

[3]. Schulz, D.J. and G.E. Robinson, Octopamine influences division of labor in honey bee colonies. J Comp Physiol A, 2001. 187(1): p. 53-61.

 Chemical & Physical Properties

Boiling Point 360.7ºC at 760 mmHg
Melting Point ~170 °C (dec.)(lit.)
Molecular Formula C8H12ClNO2
Molecular Weight 189.639
Flash Point 172ºC
Exact Mass 189.055649
PSA 66.48000
LogP 1.88660
Storage condition Desiccate at RT
Stability Stable.
Water Solubility soluble

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302 + H312 + H332
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R20/21/22
Safety Phrases S36
RIDADR 3249
WGK Germany 3
Packaging Group III
Hazard Class 6.1(b)
HS Code 2922199090

 Precursor & DownStream

Precursor  0

DownStream  2

 Customs

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles3

More Articles
Selective inhibition of adenylyl cyclase by octopamine via a human cloned alpha 2A-adrenoceptor.

Br. J. Pharmacol. 122 , 191-198, (1997)

1. In this study we have compared the abilities of the enantiomers of the structural isomers of the phenolamines, octopamine and synephrine, and the catecholamines, noradrenaline and adrenaline, to co...

Octopamine in invertebrates.

Prog. Neurobiol. 59 , 533, (1999)

Octopamine (OA), a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. It is present in relatively high concentr...

Octopamine receptors in the honey bee and locust nervous system: pharmacological similarities between homologous receptors of distantly related species.

Br. J. Pharmacol. 130 , 587-594, (2000)

Honey bees are perhaps the most versatile models to study the cellular and pharmacological basis underlying behaviours ranging from learning and memory to sociobiology. For both aspects octopamine (OA...

 Synonyms

Benzenemethanol, α-(aminomethyl)-4-hydroxy-, hydrochloride (1:1)
Octopamine hydrochloride
4-(2-amino-1-hydroxyethyl)phenol hydrochloride
Octopamine HCL
UNII:37YAS5L9HQ
(±)-Octopamine hydrochloride
DL-Octopamine hydrochloride
EINECS 212-216-4
MFCD00012881
4-(2-Amino-1-hydroxyethyl)phenol hydrochloride (1:1)
Octopamine (hydrochloride)
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Chemsrc provides Octopamine hydrochloride(CAS#:770-05-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Octopamine hydrochloride are included as well.>> amp version: Octopamine hydrochloride

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