2,3-Diaminonaphthalene

Modify Date: 2024-01-04 17:48:07

2,3-Diaminonaphthalene structure	Common Name	2,3-Diaminonaphthalene
	CAS Number	771-97-1	Molecular Weight	158.200
	Density	1.2±0.1 g/cm3	Boiling Point	370.6±15.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₀N₂	Melting Point	197-203 °C
	MSDS	Chinese USA	Flash Point	212.3±19.9 °C
	Symbol	GHS07	Signal Word	Warning

Use of 2,3-Diaminonaphthalene

2,3 Diaminonaphthalene is a highly selective colorimetric and fluorometric reagent for selenium detection and also used for the fluorometric determination of nitrite.

Name	2,3-diaminonaphthalene
Synonym	More Synonyms

Description	2,3 Diaminonaphthalene is a highly selective colorimetric and fluorometric reagent for selenium detection and also used for the fluorometric determination of nitrite.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others Dye Reagents
In Vitro	Poly(2,3-diaminonaphthalene) microspheres as a novel quencher for fluorescence-enhanced nucleic acid detection[1]. 2,3-Diaminonaphthalene (DAN) is possibly a carcinogenic reagent[2].
Kinase Assay	Various concentrations of each drug are incubated for 60 min at 37°C in OS-mL reaction volumes containing PBS (pH 7.4), 200 μM 2,3-Diaminonaphthalene (DAN) and 40 μM Sp/NO. Spermine/NO will spontaneously decompose at pH7.4 to produce 2 mol of NO and 1 mol of spermine with a half-life of 39 min at 37°C. Following the incubation period, 2.5 mL of 10 mM NaOH is added to each tube to stop the reaction. The NO-dependent N-nitrosation of 2,3-Diaminonaphthalene to yield its highly fluorescent N-nitrosated derivative, 2,3-naphthotriazole, is quantified by measuring the fluorescence of each sample using an excitation wavelength of 375 nm and an emission wavelength of 450nm. The concentration of Triazole is determined using standards of the pure 2,3-naphthotriazole[3].
References	[1]. Tian J, et al. Poly(2,3-diaminonaphthalene) microspheres as a novel quencher for fluorescence-enhanced nucleic acid detection. Analyst. 2011 Jun 7;136(11):2221-4. [2]. Martínez-Tomé MJ, et al. Immobilization and characterization of 2,3-diaminonaphthalene/cyclodextrin complexes in a sol-gel matrix: a new fluorimetric sensor for nitrite. J Fluoresc. 2009 Jan;19(1):119-25. [3]. Grisham MB, et al. Effects of aminosalicylates and immunosuppressive agents on nitric oxide-dependent N-nitrosation reactions. Biochem Pharmacol. 1994 May 18;47(10):1897-902.

Density	1.2±0.1 g/cm3
Boiling Point	370.6±15.0 °C at 760 mmHg
Melting Point	197-203 °C
Molecular Formula	C₁₀H₁₀N₂
Molecular Weight	158.200
Flash Point	212.3±19.9 °C
Exact Mass	158.084396
PSA	52.04000
LogP	1.28
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.757
Storage condition	Refrigerator
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

2,3-Diaminonaphthalene MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22;R36/37/38
Safety Phrases	S26
RIDADR	2811
WGK Germany	3
HS Code	2921590090

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DownStream 9
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HS Code	2921590090
Summary	2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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2,3-Naphthalenediamine

naphthalene-2,3-diamine

2,3-Diaminonaphthalene

EINECS 212-241-0

MFCD00004116