FKK

Modify Date: 2023-01-16 11:27:03

FKK Structure
FKK structure
Common Name FKK
CAS Number 78299-79-3 Molecular Weight 329.23
Density N/A Boiling Point N/A
Molecular Formula C17H17BrN2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FKK


FKK is an indazole derivative and also a novel bronchodilator.

 Names

Name FKK
Synonym More Synonyms

 FKK Biological Activity

Description FKK is an indazole derivative and also a novel bronchodilator.
Related Catalog
In Vivo FKK is an indazole derivative and also a novel bronchodilator. FKK (0.1 to 3.0 mg/kg, i.v.) slightly increases respiratory frequency, left ventricular (LV) dp/dt max and myocardial contractile force. A slight increase followed by a decrease is observed in systemic blood pressure and LV systolic pressure. FKK causes direct vasodilation in the coronary, mesenteric and femoral vasculatures, but has no effect on the renal vasculature. It is particularly pertinent that FKK (30 mg/kg, i.d., enough to cause marked bronchodilation), unlike aminophylline (30 mg/kg, i.d.), does not significantly influence the cardiovascular system[1].
References

[1]. Shiraki Y, et al. Effects of an indazole derivative, FKK, a novel bronchodilator, on the cardiovascular system in dogs. Arch Int Pharmacodyn Ther. 1985 Jan;273(1):155-66.

 Chemical & Physical Properties

Molecular Formula C17H17BrN2
Molecular Weight 329.23
Storage condition 2-8℃

 Synonyms

7-Methyl-9-phenyl-2,3-dihydro-1H-pyrazolo[1,2-a]indazol-10-ium bromide hydrate (1:1:1)
1H-Pyrazolo[1,2-a]indazol-10-ium, 2,3-dihydro-7-methyl-9-phenyl-, bromide, hydrate (1:1:1)
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