2-Hydroxy-4-methylbenzenesulphonic acid ammonium

Modify Date: 2024-09-19 21:45:23

2-Hydroxy-4-methylbenzenesulphonic acid ammonium Structure
2-Hydroxy-4-methylbenzenesulphonic acid ammonium structure
Common Name 2-Hydroxy-4-methylbenzenesulphonic acid ammonium
CAS Number 79093-71-3 Molecular Weight 205.23200
Density N/A Boiling Point 444.2ºC at 760 mmHg
Molecular Formula C7H11NO4S Melting Point N/A
MSDS N/A Flash Point 222.5ºC

 Use of 2-Hydroxy-4-methylbenzenesulphonic acid ammonium


2-Hydroxy-4-methylbenzenesulphonic acid ammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability[1].

 Names

Name azanium,2-hydroxy-4-methylbenzenesulfonate
Synonym More Synonyms

  Biological Activity

Description 2-Hydroxy-4-methylbenzenesulphonic acid ammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability[1].
Related Catalog
References

[1]. Deng-wei Wu, et al. Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells. Acta Pharmacol Sin. 2015 Sep;36(9):1126-36.

 Chemical & Physical Properties

Boiling Point 444.2ºC at 760 mmHg
Molecular Formula C7H11NO4S
Molecular Weight 205.23200
Flash Point 222.5ºC
Exact Mass 205.04100
PSA 86.22000
LogP 2.35200

 Safety Information

Hazard Codes Xi

 Synonyms

azanium 2-hydroxy-4-methylbenzenesulfonate
Ammonium 2-hydroxy-4-methylbenzenesulphonate
Benzenesulfonic acid,2-hydroxy-4-methyl-,ammonium salt (1:1)
EINECS 279-057-0
Benzenesulfonicacid,2-hydroxy-4-methyl-,monoammonium salt (9CI)
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