79093-71-3

79093-71-3 structure

Name: 2-Hydroxy-4-methylbenzenesulphonic acid ammonium
Chemical Name: azanium,2-hydroxy-4-methylbenzenesulfonate
CAS Number: 79093-71-3
Molecular Formula: C₇H₁₁NO₄S
Molecular Weight: 205.23200
Catalog: Research Areas Infection
Create Date: 2016-04-15 10:03:29
Modify Date: 2024-09-19 21:45:23
2-Hydroxy-4-methylbenzenesulphonic acid ammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability[1].

Name	azanium,2-hydroxy-4-methylbenzenesulfonate
Synonyms	azanium 2-hydroxy-4-methylbenzenesulfonate Ammonium 2-hydroxy-4-methylbenzenesulphonate Benzenesulfonic acid,2-hydroxy-4-methyl-,ammonium salt (1:1) EINECS 279-057-0 Benzenesulfonicacid,2-hydroxy-4-methyl-,monoammonium salt (9CI)

Description	2-Hydroxy-4-methylbenzenesulphonic acid ammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability[1].
Related Catalog	Research Areas >> Infection
References	[1]. Deng-wei Wu, et al. Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells. Acta Pharmacol Sin. 2015 Sep;36(9):1126-36.

Hazard Codes	Xi