Hydrazinecarboselenoamide,N,N-dimethyl-2-[1-(2-pyridinyl)ethylidene]-
Modify Date: 2023-01-20 09:22:56
![Hydrazinecarboselenoamide,N,N-dimethyl-2-[1-(2-pyridinyl)ethylidene]- Structure](https://www.chemsrc.com/caspic/128/79514-49-1.png)
Hydrazinecarboselenoamide,N,N-dimethyl-2-[1-(2-pyridinyl)ethylidene]- structure
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Common Name | Hydrazinecarboselenoamide,N,N-dimethyl-2-[1-(2-pyridinyl)ethylidene]- | ||
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| CAS Number | 79514-49-1 | Molecular Weight | 270.21300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H15N4Se | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Hydrazinecarboselenoamide,N,N-dimethyl-2-[1-(2-pyridinyl)ethylidene]-Ap44mSe is a selenosemicarbazone that effectively depletes cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regulation, and increased expression of the potent metastasis suppressor, N-myc downstream regulated gene-1. Ap44mSe forms redox active Cu complexes that target the lysosome to induce lysosomal membrane permeabilization[1]. |
| Name | 1-λ1-selanyl-N,N-dimethyl-N'-[(E)-1-pyridin-2-ylethylideneamino]methanimidamide |
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| Synonym | More Synonyms |
| Description | Ap44mSe is a selenosemicarbazone that effectively depletes cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regulation, and increased expression of the potent metastasis suppressor, N-myc downstream regulated gene-1. Ap44mSe forms redox active Cu complexes that target the lysosome to induce lysosomal membrane permeabilization[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C10H15N4Se |
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| Molecular Weight | 270.21300 |
| Exact Mass | 271.04600 |
| PSA | 40.52000 |
| LogP | 0.71610 |
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Hydrazinecarbos... CAS#:79514-49-1 |
| Literature: Klayman; Scovill; Bartosevich; Mason European Journal of Medicinal Chemistry, 1981 , vol. 16, # 4 p. 317 - 320 |
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~%
Hydrazinecarbos... CAS#:79514-49-1 |
| Literature: Klayman; Scovill; Bartosevich; Mason European Journal of Medicinal Chemistry, 1981 , vol. 16, # 4 p. 317 - 320 |
| Precursor 2 | |
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| DownStream 0 | |
| 2-acetylpyridine-N,N-dimethylselenosemicarbazone |
| 2-acetylpyridine 4,4-dimethyl-3-selenosemicarbazone |
| 2-Acetylpyridine 4,4-dimethylselenosemicarbazone |