Hydrazinecarboselenoamide,N,N-dimethyl-2-[1-(2-pyridinyl)ethylidene]- structure
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Common Name | Hydrazinecarboselenoamide,N,N-dimethyl-2-[1-(2-pyridinyl)ethylidene]- | ||
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CAS Number | 79514-49-1 | Molecular Weight | 270.21300 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C10H15N4Se | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Hydrazinecarboselenoamide,N,N-dimethyl-2-[1-(2-pyridinyl)ethylidene]-Ap44mSe is a selenosemicarbazone that effectively depletes cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regulation, and increased expression of the potent metastasis suppressor, N-myc downstream regulated gene-1. Ap44mSe forms redox active Cu complexes that target the lysosome to induce lysosomal membrane permeabilization[1]. |
Name | 1-λ1-selanyl-N,N-dimethyl-N'-[(E)-1-pyridin-2-ylethylideneamino]methanimidamide |
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Synonym | More Synonyms |
Description | Ap44mSe is a selenosemicarbazone that effectively depletes cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regulation, and increased expression of the potent metastasis suppressor, N-myc downstream regulated gene-1. Ap44mSe forms redox active Cu complexes that target the lysosome to induce lysosomal membrane permeabilization[1]. |
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Related Catalog | |
References |
Molecular Formula | C10H15N4Se |
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Molecular Weight | 270.21300 |
Exact Mass | 271.04600 |
PSA | 40.52000 |
LogP | 0.71610 |
~% Hydrazinecarbos... CAS#:79514-49-1 |
Literature: Klayman; Scovill; Bartosevich; Mason European Journal of Medicinal Chemistry, 1981 , vol. 16, # 4 p. 317 - 320 |
~% Hydrazinecarbos... CAS#:79514-49-1 |
Literature: Klayman; Scovill; Bartosevich; Mason European Journal of Medicinal Chemistry, 1981 , vol. 16, # 4 p. 317 - 320 |
Precursor 2 | |
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DownStream 0 |
2-acetylpyridine-N,N-dimethylselenosemicarbazone |
2-acetylpyridine 4,4-dimethyl-3-selenosemicarbazone |
2-Acetylpyridine 4,4-dimethylselenosemicarbazone |