LTB4_20-hydroxy

Modify Date: 2024-01-10 10:40:48

LTB4_20-hydroxy Structure
LTB4_20-hydroxy structure
Common Name LTB4_20-hydroxy
CAS Number 79516-82-8 Molecular Weight 352.465
Density 1.1±0.1 g/cm3 Boiling Point 581.8±50.0 °C at 760 mmHg
Molecular Formula C20H32O5 Melting Point N/A
MSDS N/A Flash Point 319.7±26.6 °C

 Use of LTB4_20-hydroxy


20-Hydroxy-leukotriene B4 is an endogenous metabolite present in Urine that can be used for the research of Sjogren Larsson Syndrome[1][2].

 Names

Name (5s,12r)-5,12,20-trihydroxy-(6z,8e,10e,14z)-eicosatetraenoic acid
Synonym More Synonyms

 LTB4_20-hydroxy Biological Activity

Description 20-Hydroxy-leukotriene B4 is an endogenous metabolite present in Urine that can be used for the research of Sjogren Larsson Syndrome[1][2].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  

[2]. Willemsen MA, et al. Defective metabolism of leukotriene B4 in the Sjögren-Larsson syndrome. J Neurol Sci. 2001 Jan 15;183(1):61-7.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 581.8±50.0 °C at 760 mmHg
Molecular Formula C20H32O5
Molecular Weight 352.465
Flash Point 319.7±26.6 °C
Exact Mass 352.224976
PSA 97.99000
LogP 2.05
Vapour Pressure 0.0±3.7 mmHg at 25°C
Index of Refraction 1.542

 Safety Information

Hazard Codes F: Flammable;Xi: Irritant;
Risk Phrases 11-36/37/38
Safety Phrases 16-26-36
RIDADR UN 1170 3/PG 2

 Synthetic Route

 Synonyms

20-hydroxy-leukotriene B4
20-Hydroxy-LTB4
20-hydroxyleukotriene
hydroxyleukotriene B4
(5S,6Z,8E,10E,12R,14Z)-5,12,20-Trihydroxy-6,8,10,14-icosatetraenoic acid
LTB4_20-hydroxy
20-OH-LTB4
5S,12R,20-TRIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENOIC ACID
6,8,10,14-Eicosatetraenoic acid, 5,12,20-trihydroxy-, (5S,6Z,8E,10E,12R,14Z)-
MFCD00065858