79516-82-8

79516-82-8 structure

Name: LTB4_20-hydroxy
Chemical Name: (5s,12r)-5,12,20-trihydroxy-(6z,8e,10e,14z)-eicosatetraenoic acid
CAS Number: 79516-82-8
Molecular Formula: C₂₀H₃₂O₅
Molecular Weight: 352.465
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-05-27 08:00:00
Modify Date: 2024-01-10 10:40:48
20-Hydroxy-leukotriene B4 is an endogenous metabolite present in Urine that can be used for the research of Sjogren Larsson Syndrome[1][2].

Name	(5s,12r)-5,12,20-trihydroxy-(6z,8e,10e,14z)-eicosatetraenoic acid
Synonyms	20-hydroxy-leukotriene B4 20-Hydroxy-LTB4 20-hydroxyleukotriene hydroxyleukotriene B4 (5S,6Z,8E,10E,12R,14Z)-5,12,20-Trihydroxy-6,8,10,14-icosatetraenoic acid LTB4_20-hydroxy 20-OH-LTB4 5S,12R,20-TRIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENOIC ACID 6,8,10,14-Eicosatetraenoic acid, 5,12,20-trihydroxy-, (5S,6Z,8E,10E,12R,14Z)- MFCD00065858

Description	20-Hydroxy-leukotriene B4 is an endogenous metabolite present in Urine that can be used for the research of Sjogren Larsson Syndrome[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology
Target	Human Endogenous Metabolite
In Vitro	Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References	[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [2]. Willemsen MA, et al. Defective metabolism of leukotriene B4 in the Sjögren-Larsson syndrome. J Neurol Sci. 2001 Jan 15;183(1):61-7.