Pirlimycin

Modify Date: 2024-01-05 18:56:39

Pirlimycin Structure
Pirlimycin structure
Common Name Pirlimycin
CAS Number 79548-73-5 Molecular Weight 410.96
Density 1.31g/cm3 Boiling Point 643.9ºC at 760 mmHg
Molecular Formula C17H31ClN2O5S Melting Point N/A
MSDS N/A Flash Point 343.2ºC

 Use of Pirlimycin


Pirlimycin (RU 38882), a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome[1].

 Names

Name (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-4-ethylpiperidine-2-carboxamide
Synonym More Synonyms

 Pirlimycin Biological Activity

Description Pirlimycin (RU 38882), a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome[1].
Related Catalog
References

[1]. Birkenmeyer RD, et, al. Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. J Med Chem. 1984 Feb;27(2):216-23.

 Chemical & Physical Properties

Density 1.31g/cm3
Boiling Point 643.9ºC at 760 mmHg
Molecular Formula C17H31ClN2O5S
Molecular Weight 410.96
Flash Point 343.2ºC
Exact Mass 410.16400
PSA 136.35000
LogP 0.76700
Index of Refraction 1.574

 Synonyms

Pirlimycin
UNII-LM19JT6G5K
Pirlimycinum
Pirlimycine
Pirlimycina