Zingibroside R1

Modify Date: 2024-01-05 10:57:55

Zingibroside R1 structure	Common Name	Zingibroside R1
	CAS Number	80930-74-1	Molecular Weight	794.96500
	Density	1.37±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₄₂H₆₆O₁₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Zingibroside R1

Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity[1].Zingibroside R1 possesses some anti-HIV-1 activity.Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM)[2].

Name	28-O-deglucosyl-chikusetsusaponin V
Synonym	More Synonyms

Description	Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity[1].Zingibroside R1 possesses some anti-HIV-1 activity.Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM)[2].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Research Areas >> Metabolic Disease
Target	IC50: 91.3 μM (2-DG uptake)[1]
References	[1]. Yoshizaki K, et al. Saponins composition of rhizomes, taproots, and lateral roots of Satsuma-ninjin (Panax japonicus). Chem Pharm Bull (Tokyo). 2013;61(3):344-50. Epub 2012 Dec 28 [2]. Hasegawa H, et al. Inhibitory effect of some triterpenoid saponins on glucose transport in tumor cells and its application to in vitro cytotoxic and antiviral activities. Planta Med. 1994 Jun;60 (3):240-3.

Density	1.37±0.1 g/cm3
Molecular Formula	C₄₂H₆₆O₁₄
Molecular Weight	794.96500
Exact Mass	794.44500
PSA	232.90000
LogP	2.97430
Storage condition	2-8℃
Water Solubility	Insuluble (1.8E-4 g/L) (25 ºC)