Amino-PEG8-amine

Modify Date: 2024-01-09 16:02:40

Amino-PEG8-amine Structure
Amino-PEG8-amine structure
Common Name Amino-PEG8-amine
CAS Number 82209-36-7 Molecular Weight 412.519
Density 1.1±0.1 g/cm3 Boiling Point 493.4±40.0 °C at 760 mmHg
Molecular Formula C18H40N2O8 Melting Point N/A
MSDS N/A Flash Point 244.7±21.0 °C

 Use of Amino-PEG8-amine


Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 3,6,9,12,15,18,21,24-Octaoxahexacosane-1,26-diamine
Synonym More Synonyms

 Amino-PEG8-amine Biological Activity

Description Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 493.4±40.0 °C at 760 mmHg
Molecular Formula C18H40N2O8
Molecular Weight 412.519
Flash Point 244.7±21.0 °C
Exact Mass 412.278473
LogP -3.73
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.467
Storage condition 2-8°C

 Synonyms

3,6,9,12,15,18,21,24-Octaoxahexacosane-1,26-diamine
MFCD28122964
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