Boc-L-3-Bromophenylalanine

Modify Date: 2024-01-02 10:52:02

Boc-L-3-Bromophenylalanine Structure
Boc-L-3-Bromophenylalanine structure
Common Name Boc-L-3-Bromophenylalanine
CAS Number 82278-73-7 Molecular Weight 344.201
Density 1.4±0.1 g/cm3 Boiling Point 475.3±40.0 °C at 760 mmHg
Molecular Formula C14H18BrNO4 Melting Point 106.1ºC
MSDS N/A Flash Point 241.2±27.3 °C

 Use of Boc-L-3-Bromophenylalanine


Boc-Phe(3-Br)-OH is a phenylalanine derivative[1].

 Names

Name Boc-3-bromo-L-phenylalanine
Synonym More Synonyms

 Boc-L-3-Bromophenylalanine Biological Activity

Description Boc-Phe(3-Br)-OH is a phenylalanine derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-924.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 475.3±40.0 °C at 760 mmHg
Melting Point 106.1ºC
Molecular Formula C14H18BrNO4
Molecular Weight 344.201
Flash Point 241.2±27.3 °C
Exact Mass 343.041901
PSA 75.63000
LogP 3.73
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.551
Storage condition Store at 0°C

 MSDS

Name: (S)-N-BOC-3-Bromophenylalanine, 95%, (98% E.E.) Material Safety Data Sheet
Synonym: N-tert-Butoxycarbonyl-3-Bromophenyl-L-Alanine.
CAS: 82278-73-7
Section 1 - Chemical Product MSDS Name: (S)-N-BOC-3-Bromophenylalanine, 95%, (98% E.E.) Material Safety Data Sheet
Synonym: N-tert-Butoxycarbonyl-3-Bromophenyl-L-Alanine.
SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
82278-73-7 (S)-N-BOC-3-Bromophenylalanine 95% unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.
SECTION 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW The toxicological properties of this material have not been fully investigated. Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.
SECTION 4 - FIRST AID MEASURES
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
SECTION 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation.
SECTION 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 82278-73-7: Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: white to off-white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 106.1 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C14H18BrNO4
Molecular Weight: 344.21
SECTION 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, dust generation.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported
SECTION 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 82278-73-7 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
(S)-N-BOC-3-Bromophenylalanine - Not listed by ACGIH, IARC, or NTP.
SECTION 12 - ECOLOGICAL INFORMATION
SECTION 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations.
SECTION 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material.
SECTION 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 82278-73-7: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 82278-73-7 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 82278-73-7 is not listed on the TSCA inventory. It is for research and development use only.
SECTION 16 - ADDITIONAL INFORMATION
MSDS Creation Date: 1/16/2002 Revision #2 Date: 10/05/2004 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages.

SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi
Safety Phrases S24/25
HS Code 2924299090

 Synthetic Route

~95%

Boc-L-3-Bromophenylalanine Structure

Boc-L-3-Bromoph...

CAS#:82278-73-7

Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 3 p. 203 - 206

~17%

Boc-L-3-Bromophenylalanine Structure

Boc-L-3-Bromoph...

CAS#:82278-73-7

Literature: US2006/69286 A1, ; Page/Page column 20 ; US 20060069286 A1

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Boc-D-3-Bromophenylalanine
(S)-N-BOC-3-Bromophenylalanine ee
N-Boc-(S)-3-bromophenylalanine
3-Bromo-N-(tert-butoxycarbonyl)-L-phenylalanine
(S)-3-(3-Bromo-phenyl)-2-tert-butoxycarbonylamino-propionic acid
(R)-3-(3-Bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid
BOC-D-3-BR-PHE-OH
Boc-L-3-Br-Phe-OH
Boc-D-3-Bromophe
N-Boc-(R)-3-bromophenylalanine
(2S)-3-(3-bromophenyl)-2-(tert-butoxycarbonylamino)propionic acid
(S)-N-Boc-3-Bromophenylalanine
BOC-M-BROMO-D-PHE-OH
N-Boc-3-broMo-L-phenylalanine
(r)-n-boc-3-bromophenylalanine
BOC-L-3-BROMOPHE
N-Boc-L-3-bromophenylalanine
MFCD01317710
BOC-S-PHE(3-BR)-OH
(S)-3-(3-bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid
(S)-3-(3-bromo-phenyl)-2-tert-butoxycarbonylamino-propinic acid
L-Phenylalanine, 3-bromo-N-[(1,1-dimethylethoxy)carbonyl]-
(2S)-3-(3-Bromophenyl)-2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid
Boc-3-bromo-D-phenylalanine
3-Bromo-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine
BOC-PHE(3-BR)-OH
(2S)-3-(3-bromophenyl)-2-[(tert-butoxycarbonyl)amino]propanoic acid
(2R)-3-(3-bromophenyl)-2-[(tert-butoxycarbonyl)amino]propanoic acid
Boc-L-3-Bromophenylalanine
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