Gomisin M2

Modify Date: 2024-01-02 11:49:14

Gomisin M2 structure	Common Name	Gomisin M2
	CAS Number	82425-45-4	Molecular Weight	386.438
	Density	1.2±0.1 g/cm3	Boiling Point	558.7±50.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₆O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	291.7±30.1 °C

Use of Gomisin M2

Gomisin M2 ((+)-Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC50 of 2.4 μM). Gomisin M2 exhibits anti-cancer and anti-allergic activities and has the potential for Alzheimer’s disease research[1][2].

Name	(6S,7R)-1,2,3-Trimethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3', 4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-13-ol
Synonym	More Synonyms

Description	Gomisin M2 ((+)-Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC50 of 2.4 μM). Gomisin M2 exhibits anti-cancer and anti-allergic activities and has the potential for Alzheimer’s disease research[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	HIV:2.4 μM (EC50)
References	[1]. Min Chen, et al. Rubrisandrins A and B, Lignans and Related anti-HIV Compounds From Schisandra Rubriflora. J Nat Prod. 2006 Dec;69(12):1697-701. [2]. Hima Dhakal, et al. Gomisin M2 Inhibits Mast Cell-Mediated Allergic Inflammation via Attenuation of FcεRI-Mediated Lyn and Fyn Activation and Intracellular Calcium Levels. Front Pharmacol. 2019 Aug 2;10:869.

Density	1.2±0.1 g/cm3
Boiling Point	558.7±50.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₆O₆
Molecular Weight	386.438
Flash Point	291.7±30.1 °C
Exact Mass	386.172943
PSA	66.38000
LogP	5.34
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.564