WDR5-0102
Modify Date: 2024-07-17 23:00:56
WDR5-0102 structure
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Common Name | WDR5-0102 | ||
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| CAS Number | 824960-50-1 | Molecular Weight | 374.82 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H19ClN4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of WDR5-0102WDR5-0102 is an inhibitor targeting WDR5-MLL1 interface (Kdis=7 μM, Kd=4 μM). WDR5-0102 suppresses MLL1 HMT activity, but not human H3K4 methyltransferase SETD7 and six other HMTs: G9a, EHMT1, SUV39H2, SETD8, PRMT3, and PRMT5[1][2]. |
| Name | WDR5-0102 |
|---|
| Description | WDR5-0102 is an inhibitor targeting WDR5-MLL1 interface (Kdis=7 μM, Kd=4 μM). WDR5-0102 suppresses MLL1 HMT activity, but not human H3K4 methyltransferase SETD7 and six other HMTs: G9a, EHMT1, SUV39H2, SETD8, PRMT3, and PRMT5[1][2]. |
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| References |
| Molecular Formula | C18H19ClN4O3 |
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| Molecular Weight | 374.82 |