Methylpseudolarate B

Modify Date: 2024-01-12 20:28:39

Methylpseudolarate B Structure
Methylpseudolarate B structure
Common Name Methylpseudolarate B
CAS Number 82508-34-7 Molecular Weight 402.481
Density 1.2±0.1 g/cm3 Boiling Point 528.8±50.0 °C at 760 mmHg
Molecular Formula C23H30O6 Melting Point N/A
MSDS N/A Flash Point 228.0±30.2 °C

 Use of Methylpseudolarate B


Methyl pseudolarate B, a natural diterpenoid, is a protein tyrosine phosphatase 1B (PTP1B) (Phosphatase) inhibitor with an IC50 value of 10.9 μM[1].

 Names

Name Methyl (1R,7S,8S,9R)-7-acetoxy-9-[(1E,3E)-5-methoxy-4-methyl-5-oxo-1,3-pentadien-1-yl]-9-methyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-ene-4-carboxylate
Synonym More Synonyms

 Methylpseudolarate B Biological Activity

Description Methyl pseudolarate B, a natural diterpenoid, is a protein tyrosine phosphatase 1B (PTP1B) (Phosphatase) inhibitor with an IC50 value of 10.9 μM[1].
Related Catalog
Target

IC50: 10.9 μM (PTP1B)[1]

References

[1]. Chun Lei, et al. New triterpenoids and PTP1B inhibitory constituents of Pseudolarix amabilis. Fitoterapia. 2019 Nov;139:104414.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 528.8±50.0 °C at 760 mmHg
Molecular Formula C23H30O6
Molecular Weight 402.481
Flash Point 228.0±30.2 °C
Exact Mass 402.204254
PSA 105.20000
LogP 4.00
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.543

 Safety Information

Hazard Codes Xi

 Synonyms

Methyl (2E,4E)-5-[(1R,7S,8S,9R)-7-acetoxy-4,9-dimethyl-11-oxo-10-oxatricyclo[6.3.2.0]tridec-3-en-9-yl]-2-methyl-2,4-pentadienoate
1H-4,9a-Ethanocyclohepta[c]pyran-7-carboxylic acid, 4a-(acetyloxy)-3,4,4a,5,6,9-hexahydro-3-[(1E,3E)-5-methoxy-4-methyl-5-oxo-1,3-pentadien-1-yl]-3-methyl-1-oxo-, methyl ester, (3R,4S,4aS,9aR)-
2,4-Pentadienoic acid, 5-[(3R,4S,4aS,9aR)-4a-(acetyloxy)-3,4,4a,5,6,9-hexahydro-3,7-dimethyl-1-oxo-1H-4,9a-ethanocyclohepta[c]pyran-3-yl]-2-methyl-, methyl ester, (2E,4E)-
Methyl (1R,7S,8S,9R)-7-acetoxy-9-[(1E,3E)-5-methoxy-4-methyl-5-oxo-1,3-pentadien-1-yl]-9-methyl-11-oxo-10-oxatricyclo[6.3.2.0]tridec-3-ene-4-carboxylate
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