Fmoc-ser-ome

Modify Date: 2024-01-02 11:27:38

Fmoc-ser-ome Structure
Fmoc-ser-ome structure
 Common Name Fmoc-ser-ome
CAS Number 82911-78-2 Molecular Weight 341.358
Density 1.3±0.1 g/cm3 Boiling Point 579.4±45.0 °C at 760 mmHg
Molecular Formula C19H19NO5 Melting Point N/A
MSDS N/A Flash Point 304.2±28.7 °C

 Use of Fmoc-ser-ome


Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor[1][2].

 Names

Name (S)-Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate
Synonym More Synonyms

 Fmoc-ser-ome Biological Activity

Description Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor[1][2].
Related Catalog
References

[1]. Tamiaki H, et al. Synthesis of chlorophyll-amino acid conjugates as models for modification of proteins with chromo/fluorophores. Bioorg Med Chem. 2014 Feb 15;22(4):1421-8.

[2]. Kärkkäinen TS, et al. Iodine-mediated glycosylation en route to mucin-related glyco-aminoacids and glycopeptides. Carbohydr Res. 2008 Jul 21;343(10-11):1830-4.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 579.4±45.0 °C at 760 mmHg
Molecular Formula C19H19NO5
Molecular Weight 341.358
Flash Point 304.2±28.7 °C
Exact Mass 341.126312
PSA 88.35000
LogP 3.25
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.595
Storage condition -15°C

 Safety Information

HS Code 2924299090

 Synthetic Route

H-Ser-Ome·HCl structure

H-Ser-Ome·HCl

CAS#:5680-80-8

Fmoc-Osu structure

Fmoc-Osu

CAS#:82911-69-1

~98%

Fmoc-ser-ome Structure

Fmoc-ser-ome

CAS#:82911-78-2

Literature: Shao, Hui; Lockman, Jeffrey W.; Parquette, Jon R. Journal of the American Chemical Society, 2007 , vol. 129, # 7 p. 1884 - 1885
Fmoc-Ser-OH structure

Fmoc-Ser-OH

CAS#:73724-45-5

methyl iodide structure

methyl iodide

CAS#:74-88-4

~94%

Fmoc-ser-ome Structure

Fmoc-ser-ome

CAS#:82911-78-2

Literature: Zhang, Fa; Zhang, Wei; Zhang, Yan; Curran, Dennis P.; Liu, Gang Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2594 - 2597
diazomethane structure

diazomethane

CAS#:186581-53-3

Fmoc-Ser-OH structure

Fmoc-Ser-OH

CAS#:73724-45-5

~%

Fmoc-ser-ome Structure

Fmoc-ser-ome

CAS#:82911-78-2

Literature: Bioorganic and Medicinal Chemistry, , vol. 22, # 4 p. 1421 - 1428
l-serine methyl ester structure

l-serine methyl...

CAS#:2788-84-3

Fmoc-Osu structure

Fmoc-Osu

CAS#:82911-69-1

~80%

Fmoc-ser-ome Structure

Fmoc-ser-ome

CAS#:82911-78-2

Literature: Lapatsanis, Lucas; Milias, George; Froussios, Kleanthis; Kolovos, Miltiadis Synthesis, 1983 , # 8 p. 671 - 673
Methanol structure

Methanol

CAS#:67-56-1

Fmoc-Ser-OH structure

Fmoc-Ser-OH

CAS#:73724-45-5

~%

Fmoc-ser-ome Structure

Fmoc-ser-ome

CAS#:82911-78-2

Literature: Organic letters, , vol. 3, # 16 p. 2477 - 2479
9-Fluorenemethanol structure

9-Fluorenemethanol

CAS#:24324-17-2

~%

Fmoc-ser-ome Structure

Fmoc-ser-ome

CAS#:82911-78-2

Literature: Canadian Journal of Chemistry, , vol. 60, p. 976 - 980
dicyclohexylamine salt of N-hydroxysuccinimide structure

dicyclohexylami...

CAS#:82911-72-6

~%

Fmoc-ser-ome Structure

Fmoc-ser-ome

CAS#:82911-78-2

Literature: Canadian Journal of Chemistry, , vol. 60, p. 976 - 980
Dicyclohexylamine structure

Dicyclohexylamine

CAS#:101-83-7

~%

Fmoc-ser-ome Structure

Fmoc-ser-ome

CAS#:82911-78-2

Literature: Canadian Journal of Chemistry, , vol. 60, p. 976 - 980

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester
Methyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]serinate
methyl (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxypropanoate
Fmoc-Ser-Ome
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