Isoxazole 9 (ISX-9)
Modify Date: 2024-01-08 13:50:33
Isoxazole 9 (ISX-9) structure
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Common Name | Isoxazole 9 (ISX-9) | ||
|---|---|---|---|---|
| CAS Number | 832115-62-5 | Molecular Weight | 234.274 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 468.1±35.0 °C at 760 mmHg | |
| Molecular Formula | C11H10N2O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 236.9±25.9 °C | |
Use of Isoxazole 9 (ISX-9)ISX-9 is a small molecule inducer of adult neural stem cell differentiation. Target: At 2.5-20 μM, ISX-9 has been shown to dose-dependently trigger neurogenesis and block gliogenesis in adult rat hippocampal stem cells through a calcium-activated signaling pathway dependent on myocyte-enhancer factor 2-dependent gene expression.ISX-9 administered at 20 mg/kg for 12 days to mice has been reported to improve hippocampal function as evidenced by enhanced spatial memory ability in the Morris water maze test. |
| Name | N-Cyclopropyl-5-(2-thienyl)-1,2-oxazole-3-carboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | ISX-9 is a small molecule inducer of adult neural stem cell differentiation. Target: At 2.5-20 μM, ISX-9 has been shown to dose-dependently trigger neurogenesis and block gliogenesis in adult rat hippocampal stem cells through a calcium-activated signaling pathway dependent on myocyte-enhancer factor 2-dependent gene expression.ISX-9 administered at 20 mg/kg for 12 days to mice has been reported to improve hippocampal function as evidenced by enhanced spatial memory ability in the Morris water maze test. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 468.1±35.0 °C at 760 mmHg |
| Molecular Formula | C11H10N2O2S |
| Molecular Weight | 234.274 |
| Flash Point | 236.9±25.9 °C |
| Exact Mass | 234.046295 |
| PSA | 86.86000 |
| LogP | 1.25 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.637 |
| Storage condition | -20℃ |
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~62%
Isoxazole 9 (ISX-9) CAS#:832115-62-5 |
| Literature: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM Patent: US2009/36451 A1, 2009 ; Location in patent: Page/Page column 32 ; |
| Precursor 2 | |
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| DownStream 0 | |
| N-Cyclopropyl-5-(2-thienyl)-1,2-oxazole-3-carboxamide |
| 3-Isoxazolecarboxamide, N-cyclopropyl-5-(2-thienyl)- |
| ISX 9 |
| Isoxazole 9 |
| ISX-9 |