2,6-DIHYDROXY-ANTHRAQUINONE

Modify Date: 2024-01-02 19:39:01

2,6-DIHYDROXY-ANTHRAQUINONE structure	Common Name	2,6-DIHYDROXY-ANTHRAQUINONE
	CAS Number	84-60-6	Molecular Weight	240.211
	Density	1.5±0.1 g/cm3	Boiling Point	442.1±35.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₈O₄	Melting Point	>320 °C(lit.)
	MSDS	Chinese USA	Flash Point	235.3±22.4 °C
	Symbol	GHS07	Signal Word	Warning

Use of 2,6-DIHYDROXY-ANTHRAQUINONE

Anthraflavic acid, a flavonoid, is a potent IQ mutagenicity inhibitor by virtue of its ability to inhibit both its microsomal and cytosolic activation pathways. Anthraflavic acid is a potent and specific cytochrome P-448 inhibitor activity an enzyme system closely associated with the activation of many chemical carcinogens[1].

Name	anthraflavic acid
Synonym	More Synonyms

Description	Anthraflavic acid, a flavonoid, is a potent IQ mutagenicity inhibitor by virtue of its ability to inhibit both its microsomal and cytosolic activation pathways. Anthraflavic acid is a potent and specific cytochrome P-448 inhibitor activity an enzyme system closely associated with the activation of many chemical carcinogens[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Ayrton AD, et al. Anthraflavic acid inhibits the mutagenicity of the food mutagen IQ: mechanism of action. Mutat Res. 1988 Mar-Apr;207(3-4):121-5.

Density	1.5±0.1 g/cm3
Boiling Point	442.1±35.0 °C at 760 mmHg
Melting Point	>320 °C(lit.)
Molecular Formula	C₁₄H₈O₄
Molecular Weight	240.211
Flash Point	235.3±22.4 °C
Exact Mass	240.042252
PSA	74.60000
LogP	3.36
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.733
Stability	Stable. Incompatible with strong oxidizing agents.

2,6-DIHYDROXY-ANTHRAQUINONE MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CB6675000

CHEMICAL NAME :: Anthraquinone, 2,6-dihydroxy-

CAS REGISTRY NUMBER :: 84-60-6

BEILSTEIN REFERENCE NO. :: 2054127

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C14-H8-O4

MOLECULAR WEIGHT :: 240.22

WISWESSER LINE NOTATION :: L C666 BV IVJ DQ LQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 40,203,1976

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	CB6675000
HS Code	2914690090

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HS Code	2914690090
Summary	2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity.

Bioorg. Med. Chem. Lett. 11(14) , 1839-42, (2001)

The methanolic extract from the roots of Polygonum (P.) cuspidatum was found to enhance cell proliferation at 30 or 100 microg/mL in MCF-7, an estrogen-sensitive cell line. By bioassay-guided separati...

Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system.

Appl. Environ. Microbiol. 43(6) , 1354-9, (1982)

The mutagenicity of anthracene, anthraquinone, and four structurally similar compounds of each was evaluated in the Ames/Salmonella microsome assay. Anthraquinone was shown to be mutagenic for strains...

A compact optical instrument with artificial neural network for pH determination.

Sensors (Basel.) 12 , 6746-63, (2012)

The aim of this work was the determination of pH with a sensor array-based optical portable instrument. This sensor array consists of eleven membranes with selective colour changes at different pH int...

2,6-DIHYDROXY-ANTHRAQUINONE

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2,6-DIHYDROXY-ANTHRAQUINONE
Price: Click To Check
Purity: 90.0%
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 2,6-DIHYDROXY-ANTHRAQUINONE
Price: ￥176.0/1g ￥586.0/5g ￥76.0/250mg ￥1026.0/10g
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,6-Dihydroxy-anthraquinon
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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