Adipiplon

Modify Date: 2024-04-11 09:27:32

Adipiplon structure	Common Name	Adipiplon
	CAS Number	840486-93-3	Molecular Weight	351.38100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₈FN₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Adipiplon

Adipiplon (NG2-73) is a selective GABAA receptor positive allosteric modulator. Adipiplon is particularly useful in the treatment of a variety of central nervous system (CNS) disorders.

Name	7-[[2-(3-fluoropyridin-2-yl)imidazol-1-yl]methyl]-2-methyl-8-propyl-[1,2,4]triazolo[1,5-c]pyrimidine
Synonym	More Synonyms

Description	Adipiplon (NG2-73) is a selective GABAA receptor positive allosteric modulator. Adipiplon is particularly useful in the treatment of a variety of central nervous system (CNS) disorders.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
References	[1]. Vinkers CH, Olivier B, Hanania T, et al. Discriminative stimulus properties of GABAA receptor positive allosteric modulators TPA023, ocinaplon and NG2-73 in rats trained to discriminate chlordiazepoxide or zolpidem. Eur J Pharmacol. 2011;668(1-2):190-193. [2]. Xie, Linghong; Han, Bingsong; Xu, Yuelian. et al. Preparation of imidazo-pyrimidines and triazolo-pyrimidines as benzodiazepine receptor ligands for the treatment of central nervous system diseases. WO2005012306A2.

Description

Adipiplon (NG2-73) is a selective GABAA receptor positive allosteric modulator. Adipiplon is particularly useful in the treatment of a variety of central nervous system (CNS) disorders.

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> GABA Receptor

References

[1]. Vinkers CH, Olivier B, Hanania T, et al. Discriminative stimulus properties of GABAA receptor positive allosteric modulators TPA023, ocinaplon and NG2-73 in rats trained to discriminate chlordiazepoxide or zolpidem. Eur J Pharmacol. 2011;668(1-2):190-193.

[2]. Xie, Linghong; Han, Bingsong; Xu, Yuelian. et al. Preparation of imidazo-pyrimidines and triazolo-pyrimidines as benzodiazepine receptor ligands for the treatment of central nervous system diseases. WO2005012306A2.