(S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-N-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE

Modify Date: 2024-03-31 23:22:18

(S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-N-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE Structure
(S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-N-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE structure
Common Name (S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-N-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE
CAS Number 845745-37-1 Molecular Weight 479.06
Density N/A Boiling Point N/A
Molecular Formula C25H39ClN4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-N-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE


(S)-SW IV-52 hydrochloride is a small molecule that can induce apoptosis in ovarian cancer. (S)-SW IV-52 hydrochloride has minimal single-agent activity at concentrations up to 200 μM[1].

 Names

Name (2S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide,hydrochloride
Synonym More Synonyms

  Biological Activity

Description (S)-SW IV-52 hydrochloride is a small molecule that can induce apoptosis in ovarian cancer. (S)-SW IV-52 hydrochloride has minimal single-agent activity at concentrations up to 200 μM[1].
Related Catalog
References

[1]. Garg G, et al. Conjugation to a SMAC mimetic potentiates sigma-2 ligand induced tumor cell death in ovarian cancer. Mol Cancer. 2014 Mar 7;13:50.  

 Chemical & Physical Properties

Molecular Formula C25H39ClN4O3
Molecular Weight 479.06
Exact Mass 478.27100
PSA 90.54000
LogP 4.22260

 Synonyms

(S)-1-((S)-3,3-Dimethyl-2-((S)-2-(methylamino)propanamido)butanoyl)-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)pyrrolidine-2-carboxamide hydrochloride