Asparanin A

Modify Date: 2024-01-29 19:35:25

Asparanin A Structure
Asparanin A structure
Common Name Asparanin A
CAS Number 84633-33-0 Molecular Weight 740.91800
Density N/A Boiling Point N/A
Molecular Formula C39H64O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Asparanin A


Asparanin A is an apoptosis inducer with anticancer activity. Asparanin A induces cell cycle arrest in the G0/G1 phase through mitochondria and PI3K/AKT signaling pathways, inhibiting cancer cell growth. Asparanin A also demonstrated in vivo efficacy in a mouse xenograft model of Ishikawa endometrial carcinoma, significantly inhibiting tumor growth[1].

 Names

Name (25S)-5β-spirostan-3β-ol 3-O-β-D-glucopyranosyl-(1->2)-β-D-glucopyranoside
Synonym More Synonyms

 Asparanin A Biological Activity

Description Asparanin A is an apoptosis inducer with anticancer activity. Asparanin A induces cell cycle arrest in the G0/G1 phase through mitochondria and PI3K/AKT signaling pathways, inhibiting cancer cell growth. Asparanin A also demonstrated in vivo efficacy in a mouse xenograft model of Ishikawa endometrial carcinoma, significantly inhibiting tumor growth[1].
Related Catalog
References

[1]. Zhang F, et al. Asparanin A from Asparagus officinalis L. Induces G0/G1 Cell Cycle Arrest and Apoptosis in Human Endometrial Carcinoma Ishikawa Cells via Mitochondrial and PI3K/AKT Signaling Pathways. J Agric Food Chem. 2020 Jan 8;68(1):213-224..  

 Chemical & Physical Properties

Molecular Formula C39H64O13
Molecular Weight 740.91800
Exact Mass 740.43500
PSA 196.99000
LogP 1.44220

 Precursor & DownStream

Precursor  0

DownStream  2

 Synonyms

(25S)-5β-spirostan-3β-ol-3-O-β-D-glucopyranosyl-(1,2)-β-D-glucopyranoside
asparanin A
3-O-[β-D-glucopyranosyl(1->2)-β-D-glucopyranosyl]-(25S)-5β-spirostan-3β-ol
(25S)-5β-spirostan-3β-ol-3-O-β-D-glucopyranosyl(1->2)-β-D-glucopyranoside
3-O-β-D-glucopyranosyl-(1->2)-β-D-glucopyranosyl-5β(25S)-spirostan-3β-ol
25(S)-schidigera-saponin D5